Search for dissertations about: "vaccine response"
Showing result 1 - 5 of 245 swedish dissertations containing the words vaccine response.
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1. Heat shock proteins as vaccine adjuvants
Abstract : New efficient vaccines against infectious diseases are in demand. Some important factors impeding the vaccine development are the poor immunogenicity and the MHC restriction of the immune responses to a number of antigens. READ MORE
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2. Impact of the inflammatory response on specific immunity in neurosurgical patients
Abstract : Vaccination with a T-cell-dependent pneumococcal conjugate vaccine (PCV) followed by a T-cell-independent pneumococcal polysaccharide vaccine (PPSV) is recommended after basilar skull fracture to reduce the risk of meningitis. The optimal time frame for vaccination has not yet been established and varies widely in practice. READ MORE
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3. Development of a Cancer Vaccine Targeting Tumor Blood Vessels
Abstract : A treatment strategy for cancer is the suppression of tumor growth by directing an immune response to the tumor vessels, which will destroy the tissue.In this thesis we describe the development of a vaccine that targets antigens expressed around angiogenic vasculature in most solid tumors. READ MORE
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4. The impact of viral vaccines in immunosuppressed and at-risk individuals
Abstract : Vaccines have saved millions of lives, but for some individuals with a defective immune system the protection may be uncertain. This thesis aims to assess the immune response following viral vaccines in immunocompromised patients and in other groups at-risk. READ MORE
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5. Pneumococcal vaccination in inflammatory rheumatic disease and in splenectomy patients. From antibody response to memory cells
Abstract : Objectives:The overall aim of the dissertation is to examine antibody response to immunization with pneumococcal vaccine in patients with inflammatory rheumatic disease (IRD), in relation to disease-modifying antirheumatic drug (DMARD) treatments, and in postsplenectomy patients.Methods:(I) Splenectomized patients without previous pneumococcal conjugate vaccine (PCV) immunization were invited to receive one dose 13-valent PCV (PCV13). READ MORE