Search for dissertations about: "vagal stimulation"

Showing result 1 - 5 of 14 swedish dissertations containing the words vagal stimulation.

  2. 1. The neuromodulatory effect, safety and effectiveness of vagus nerve stimulation

    Author : David Revesz; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vagus nerve stimulation; VNS; Neuromodulation; Neurogenesis; VBLOC; Epilepsy; Depression; Safety; Efficacy; Effectiveness;

    Abstract : Vagus nerve stimulation (VNS) is an adjunctive palliative neuromodulatory treatment for drug resistant epilepsy (DRE) and chronic depression. It has also been proposed as a treatment for many other conditions such as chronic pain, heart failure, and Alzheimer’s disease. READ MORE

  4. 2. The Duodenal Mucosal Bicarbonate Secretion : Role of Melatonin in Neurohumoral Control and Cellular Signaling

    Author : Markus Sjöblom; Gunnar Flemström; Olof Nylander; Karl EO Åkerman; Per M. Hellström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; alkaline secretion; central nervous system; duodenal enterocyte; duodenal ulcer; duodenum; enterochromaffin cell; human; intraarterial; intracellular calcium; intracerebroventricular; melatonin; rat; vagal nerve; Fysiologi; Physiology; Fysiologi;

    Abstract : The duodenal lumen is exposed to aggressive factors with a high potential to cause damage to the mucosa. Bicarbonate secretion by the duodenal mucosa is accepted as the primary important defense mechanism against the hydrochloric acid intermittently expelled from the stomach. READ MORE

  5. 3. Porcine myocardial ischemia-reperfusion studies on cardioprotection, ventricular arrhythmia and electrophysiology

    Author : Jacob Odenstedt; Göteborgs universitet; []
    Keywords : porcine; myocardial ischemia; ventricular arrhythmia; sudden cardiac death; electrophysiology; vectorcardiography; endocardial mapping; spinal cord stimulation;

    Abstract : Background: Coronary artery disease is the primary cause of death in adults in the industrialised world and ventricular fibrillation associated with myocardial ischemia is the main cause of sudden cardiac death. Restoration of blood flow and preservation of myocardial integrity throughout ischemia and reperfusion is essential to improve clinical outcome. READ MORE

  6. 4. Peripherally administered choleocystokinin-8 increases neurotrophins in the brain

    Author : Paola Tirassa; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NGF; BDNF; CCK-8; glutamate; GABA; CCK receptors; hypothamalus; hippocampus; Choline Acetyltransferase; fimibria-fornix transection; vagotomy; vagal stimulation; RT-PCR; ELISA;

    Abstract : The aim of this thesis was to test the hypothesis that the gastric hormone Cholecystokinin-8 (CCK-8) can modulate the production of Nerve Growth Factor (NGF) in the brain. NGF is the first discovered and the best characterized neurotrophic factor which plays a crucial role in the survival and development of basal forebrain cholinergic neurons (BFCN). READ MORE

  7. 5. Neuronal release and function of nitric oxide in smooth muscle

    Author : Henrik H Iversen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Autonomic neurotransmission; gastrointestinal tract; nitric oxide; nitric oxidesynthase; smooth muscle; urinary tract.;

    Abstract : The aim of the present thesis was to study nitric oxide (NO) as an effector molecule in autonomic neurotransmission. The nitrergic transmitter was examined with regard to its pharmacological profile, stimuli of release, release pattern, and effects in gastrointestinal and urinary tract smooth muscle. READ MORE