Search for dissertations about: "vagus"

Showing result 6 - 10 of 29 swedish dissertations containing the word vagus.

  2. 6. An experimental study on the interaction between the neuro-endocrine and immune systems in the gastrointestinal tract

    Author : Bi-Feng Qian; Eva Ekblad; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastrointestinal tract; neuro-endocrine system; substance P; vasoactive intestinal polypeptide; vagus nerves; mucosal immune system; T lymphocytes; cytokines; inflammation; mouse;

    Abstract : The mucosa lining of the gastrointestinal (GI) tract is in immediate contact with food nutrients to allow a rapid and efficient digestion and absorption and at the same time protects against the incessant risk of attack from pathogenic microbes. Maintenance of normal physiological activities in the GI tract is dependent on a number of regulatory interactions between the nervous, endocrine, and immune systems, as well as environmental and genetic factors. READ MORE

  4. 7. Novel insights into the regulation of insulin secretion by GLP-1, GIP and glucagon

    Author : Linda Ahlkvist; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vagus nerve; GPR119; Insulin resistance; Glucagon; GIP; GLP-1; Insulin;

    Abstract : There are many contributing factors to the development of type 2 diabetes, however, failure of beta-cells to sufficiently secrete insulin is the key component. The underlying mechanism of beta-cell failure is not fully established. In this thesis, we examined the role of high glucagon levels, i.e. READ MORE

  5. 8. Studies of cytokine mediated regulation of central nervous functions : role of prostaglandins

    Author : Monica Ek; Karolinska Institutet; Karolinska Institutet; []
    Keywords : interleukin-1; prostaglandin E2; central nervous system; HPA axis; fever; vagus nerve;

    Abstract : The communication between the immune system and the central nervous system (CNS) results in an array of centrally regulated illness responses, including fever and increased hypothalamus-pituitary-adrenal (HPA) axis activity. The mechanisms by which the immune system signals the brain across the blood-brain barrier have not been completely elucidated, but proinflammatory cytokines, like interleukin-1 (IL-1), are believed to act as important mediators. READ MORE

  6. 9. Neuropeptide circuitries regulating food and water intake

    Author : Christian Broberger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : agouti gene-related protein; anorexia mutation; arcuate nucleus; cholecystokinin; cocaine- and amphetamine-regulated transcript; coexistence; confocal microscopy; dorsal root ganglion; feeding; hypocretin; immunohistochemistry; in situ hybridization; melanin-concentrating hormone; nodose ganglion; nucleus tractus solitaxii; orexin; paraventricular nucleus; satiety; sensory neurones; pro-opiomelanocortin; vagus nerve;

    Abstract : An adequate supply of nutrients through food intake is critical for survival, as evidenced by disorders such as obesity and anorexia, which in the long run may be life-threatening. Feeding behaviour is ultimately controlled by interacting neuronal populations in the brain. READ MORE

  7. 10. Neural control of inflammation

    Author : April S Caravaca; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pioneering research on neural control of inflammation has paved the way for new and exciting developments in the growing field of bioelectronic medicine. In the past couple of decades, pre-clinical research on the role of the vagus nerve in inflammation and immunity has brought electrical stimulation of select nerves into clinical trials for the treatment of chronic inflammatory diseases. READ MORE