Search for dissertations about: "vanilloid receptor"

Showing result 1 - 5 of 8 swedish dissertations containing the words vanilloid receptor.

  2. 1. Microvascular inflammatory response in the skin

    Author : Vladimir Evilevitch; Lunds universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; medicinsk instrumentering; Physiology; Fysiologi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; Clinical physics; sodium nitroprusside; terbutaline; anandamide; TRPV1; skin prick test; vanilloid receptor; skin microcirculation; laser Doppler imaging; Plasma exudation; vasodilatation;

    Abstract : This thesis examines the microvascular inflammatory response in the skin. The microvascular response includes vasodilatation and plasma exudation. In the first three studies, the combined response was measured in guinea pig skin with a technique based on detection of radiolabelled protein. READ MORE

  4. 2. Vasodilator actions of EDHF and anandamide

    Author : David Andersson; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vanilloid receptors; afferent neurons; anandamide; cannabinoids; potassium channels; hyperpolarization; vasodilation; Vascular endothelium; arteries; airways; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : Vasodilator responses to endothelium-derived hyperpolarizing factor (EDHF) and anandamide in isolated arteries were investigated. A combination of the potassium channel blockers charybdotoxin and apamin inhibits EDHF-mediated relaxations. READ MORE

  5. 3. Biosynthesis of capsaicinoids by recombinant Saccharomyces cerevisiae

    Author : Nina Muratovska; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; capsaicinoids; nonivamide; baker’s yeast; Capsicum; Saccharomyces cerevisiae; Pseudomonas putida; lignin-derived substrates; vanillin aminotransaminase; reductive amination; vanillylamine; N-Acyltransferase; CoA-ligase; amide; whole-cell bioconversion; TRPV1 receptor; ion channel; calcium dye Fluo-4; flow cytometry;

    Abstract : Throughout history, people have used products from different microorganisms and plants for many medicinal and nutritional applications. Chilli peppers have been used for spicing up food, but also for their pharmacological properties. READ MORE

  6. 4. Endogenous activators of the pain receptor TRPV1 From cell to man

    Author : Pouya Movahed Rad; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; cannabinoids; capsazepine; N-acylethanolamines; anandamide; blood Circulation; vasodilation; humans; calcitonin Gene-related Peptide; capsaicin; neurogenic inflammation; nociceptors; TRPV1 protein; pain;

    Abstract : N-acylethanolamines (NAEs) belong to a growing family of endogenous signalling molecules acting on a variety of receptors and ion channels. In 1992, it was reported that the N-acylethanolamine anandamide is present in the brain and activates the central cannabinoid (CB) receptor. READ MORE

  7. 5. Sensory neuropeptides and nitric oxide in nasal vascular regulation

    Author : Johan Rinder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Sensory nerves; neuropeptides; nasal mucosa; nitric oxide; vascular regulation; acoustic rhinometry; NK1-receptors; CGRP-receptors; vanilloid receptors; capsaicin; lactic acid; exercise; a-adrenoceptor agonists; pig; human.;

    Abstract : The role of sensory neuropeptides and nitric oxide in vascular regulation was investigated in the pig nasal mucosa in vivo using arterial blood flow measurements and acoustic rhinometry for analysis of capacitance function. Moreover, the effects of heavy physical exercise, a-adrenoceptor agonists, nitric oxide synthase (NOS) inhibition, L-arginine, nitric oxide (NO) gas, histamine and capsaicin on nasal cavity NO levels and nasal cavity volume, were investigated in healthy subjects. READ MORE