Search for dissertations about: "var PfEMP1"
Showing result 1 - 5 of 11 swedish dissertations containing the words var PfEMP1.
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1. Towards understanding the SURFIN protein family and var genes in Plasmodium falciparum
Abstract : Plasmodium falciparum, the parasite responsible for severe malaria, has been shown to use different protein families for its survival and proliferation within the human host. Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), a protein responsible for the cytoadherence of parasitized red blood cells (pRBCs) has been implicated in severe disease. READ MORE
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2. Antigenic variation and virulence in Plasmodium falciparum malaria : studies on the surface protein PfEMP1
Abstract : Approximately 40% of the world’s population is at risk of contracting malaria, a disease caused by the intracellular protozoan Plasmodium. The species Plasmodium falciparum is responsible for the majority of severe morbidity and mortality. READ MORE
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3. Genomic and transcripto variation in blood stage Plasmodium falciparum
Abstract : Malaria research has entered a postgenomic era since October 2002, when the complete genomic sequence of Plasmodium falciparum strain 3D7 was published. A massive amount of information generated by the P. falciparum genome project has facilitated the development of many novel platforms for profiling different levels of biological aspects. READ MORE
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4. Variant antigens at the infected red cell surface in Plasmodium falciparum malaria
Abstract : Disease severity in Plasmodium falciparum infections is, to a large extent, a consequence of the parasite's efficient escape from die human host defences. Sequestration and antigenic variation are two evasion mechanisms featured by P.falciparum. READ MORE
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5. Pursuing the fever trail : pathogenesis of blood-stage P. falciparum malaria and pregnancy
Abstract : The burden of the most virulent form of human malarias, Plasmodium falciparum, is concentrated among young children and pregnant women in sub-Saharan Africa. Excessive sequestration of parasite-infected red blood cells (pRBCs) in the capillary beds of different organs is the hallmark of P. READ MORE