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Showing result 1 - 5 of 84 swedish dissertations matching the above criteria.

  1. 1. Novel Statistical Methods in Quantitative Genetics : Modeling Genetic Variance for Quantitative Trait Loci Mapping and Genomic Evaluation

    Author : Xia Shen; Örjan Carlborg; Lars Rönnegård; William Hill; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; statistical genetics; quantitative trait loci; genome-wide association study; genomic selection; genetic variance; hierarchical generalized linear model; linear mixed model; random effect; heteroscedastic effects model; variance-controlling genes; Complex Systems – Microdata Analysis;

    Abstract : This thesis develops and evaluates statistical methods for different types of genetic analyses, including quantitative trait loci (QTL) analysis, genome-wide association study (GWAS), and genomic evaluation. The main contribution of the thesis is to provide novel insights in modeling genetic variance, especially via random effects models. READ MORE

  2. 2. Towards the Inclusion of Pelvis Population Variance in Human Body Models

    Author : Erik Brynskog; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Finite Element Human Body Model; Sparse Principal Component Analysis; Global Sensitivity Analysis; Pelvis; Population Variance;

    Abstract : With a future large-scale introduction of autonomous vehicles, the proportion of intersection crashes on the total number of motor vehicle crashes is expected to increase. The pelvis is frequently exposed to high loads in several of these impacts. READ MORE

  3. 3. Semi-Markov Models for Insurance and Option Rewards

    Author : Fredrik Stenberg; Dmitrii Silvestrov; Kimmo Eriksson; Nikolaos Limnios; Mälardalens högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; semi-Markov process; discrete time; insurance; actuarial; higher order reward; disability; variance; skewness; kurtosis; reward process; stochastic volatility; controlling semi-Markov process; Monte Carlo algorithm; convergence; optimal stopping; skeleton approximation; regime switching; semi-Markov modulated; European option; American option; Lévy process.; MATHEMATICS; MATEMATIK; Matematik tillämpad matematik;

    Abstract : This thesis presents studies of semi-Markov models for insurance and option rewards. The thesis consists of the introduction and six papers. The introduction presents the results of the thesis in an informal way.In paper A, a general semi-Markov reward model is presented. READ MORE

  4. 4. Robust Design Experimentation and Dispersion Effects

    Author : Martin Arvidsson; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; estimation procedure; design of experiments; generalized linear models; event matrices; variance component; location effects; split-plot experiments; robust design; identification procedure; dispersion effects;

    Abstract : One of the most common methods in robust design methodology is design of experiments. This method makes it possible to identify settings of design factors that make products and production processes robust with respect to noise factors. READ MORE

  5. 5. Development of Variance Component Methods for Genetic Dissection of Complex Traits

    Author : Francois Besnier; Örjan Calborg; Miguel Perez-Enciso; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioinformatics; Bioinformatik; Genetik; Genetics;

    Abstract : This thesis presents several developments on Variance component (VC) approach for Quantitative Trait Locus (QTL) mapping. The first part consists of methodological improvements: a new fast and efficient method for estimating IBD matrices, have been developed. READ MORE