Search for dissertations about: "vascular cells"
Showing result 11 - 15 of 662 swedish dissertations containing the words vascular cells.
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11. Transcriptional and post-transcriptional regulation of vascular smooth muscle cell phenotype - Implications for vascular disease states
Abstract : As the world population is pushing toward 8 billion, cardiovascular diseases (CVD) remain the leading cause of death worldwide, representing 30% of all global deaths. A large body of work has recognized that smooth muscle cells (SMCs) surrounding the blood vessels play a prominent role in the development and progression of cardiovascular diseases. READ MORE
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12. Biomarkers of vascular function and structure in young healthy adults
Abstract : Atherosclerosis is a disease affecting the blood vessels in the body. Its pathophysiologic mechanisms involve infiltration of the vessel walls by fatty matter and immune cells. This process is slow, starting in childhood but typically not manifesting as symptomatic disease until late adulthood (after 60 years of age). READ MORE
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13. Vascular Effects of P2 Receptors. Changes in Congestive Heart Failure
Abstract : Extracellular nucleotides induce dilatation and constriction of blood vessels by activation of P2 receptors. In this thesis the vasomotor effects of P2 receptor activation were studied in the rat mesenteric artery, and their changes in congestive heart failure (CHF) were evaluated using in vitro pharmacology, electrophysiology and competitive RT-PCR. READ MORE
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14. From endothelial cells to the vascular network : How cell migration and proliferation are orchestrated to build lymphatic vessels
Abstract : Lymphatic endothelial cells (LECs) migrate across body to form a branched network, which is crucial for fluid drainage and immune cell trafficking of the tissues. However, the molecular mechanisms behind the spatiotemporal regulation and fine-tuning of LEC migration remain largely unknown. READ MORE
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15. Experimental Studies of Endocrine Disrupting Compounds in Vascular Cells and Tissues
Abstract : Epidemiological evidence suggest that exposure to endocrine disrupting compounds (EDCs) is a risk factor for diseases that involves the cardiovascular system but we know little about the mechanisms whereby these compounds can cause injury in the vasculature. The aim of this thesis was to characterize the effects and mechanisms of some EDCs in vascular cells and highly vascularized tissues. READ MORE