Search for dissertations about: "vascular dementia"

Showing result 1 - 5 of 76 swedish dissertations containing the words vascular dementia.

  1. 1. Predictors of Dementia : Insulin, Fatty Acids and Vascular Risk Factors

    Author : Elina Rönnemaa; Lena Kilander; Lars Lannfelt; Björn Zethelius; Laura Fratiglioni; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; dementia; Alzheimer’s disease; vascular dementia; insulin secretion; diabetes; fatty acids; epidemiology; vascular risk factors; Geriatrics; Geriatrik;

    Abstract : Identification of modifiable risk factors for Alzheimer’s disease (AD) is crucial in order to diminish suffering from this devastating disease. The aim of this thesis was to investigate if different aspects of glucose metabolism, insulin, fatty-acid composition or other vascular risk factors predict the future development of AD and dementia. READ MORE

  2. 2. Dementia Proteomics

    Author : Julia Remnestål; Peter Nilsson; Anna Månberg; Pieter Jelle Visser; KTH; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Dementia; Proteomics; Alzheimer s disease; Frontotemporal dementia; Antibody array; Suspension bead array; Cerebrospinal fluid; Protein profiling; Biomarker discovery; Biotechnology; Bioteknologi;

    Abstract : The term dementia encompass a number of conditions arising as a consequence of tissue degeneration in the brain. This degeneration is caused by molecular events occurring on a cellular level including inflammation, defective waste disposal and accumulation of insoluble proteins and peptides. READ MORE

  3. 3. Biochemical markers in dementia - Exploring Swedish registry data and the human proteome

    Author : Tobias Skillbäck; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; Dementia; Alzheimer s disease; Vascular dementia; Creutzfeldt Jakob disease; Lewy body dementia; Frontotemporal dementia; Parkinson s disease dementia;

    Abstract : Cerebrospinal fluid (CSF) biomarkers of neurodegenerative diseases have a wide scope of applications in diagnostics, prognosis assessment, disease staging, treatment evaluation and more. In this PhD project we aimed to expand the understanding of the properties of known CSF biomarkers of Alzheimer’s disease (AD) and other neurodegenerative diseases, including the most prevalent dementia disorders. READ MORE

  4. 4. Comorbidity and vascular risk factors  associated with idiopathic normal pressure hydrocephalus : the INPH-CRasH Study

    Author : Hanna Israelsson Larsen; Jan Malm; Anders Eklund; Norman Relkin; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hydrocephalus; normal pressure; vascular disease; vascular risk factors; elderly; depression; case control study; epidemiology; dementia; vascular dementia; small vessel disease; cerebrovascular disease; transient ischemic attack; Neurology; neurologi;

    Abstract : Idiopathic normal pressure hydrocephalus (INPH) is a dementia treatable by insertion of a cerebrospinal fluid shunt. It has been suggested that INPH has similar pathophysiological mechanisms as cerebrovascular disease, but the vascular risk factor (VRF) profile of INPH patients has not been assessed using a modern epidemiological approach. READ MORE

  5. 5. Vascular mechanisms in dementia with special reference to folate and fibrinolysis

    Author : Nils-Olof Hagnelius; Torbjörn K. Nilsson; Teodoro Bottiglieri; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dementia; Alzheimer’s disease; vascular dementia; folate; homocysteine; vitamin B12; CSF Serum folate ratio; fibrinolysis; tPA; PAI-1; Geriatrics and medical gerontology; Geriatrik och medicinsk gerontologi; MEDICINE; MEDICIN; Geriatrik; Geriatrics; Medicin; Medicine;

    Abstract : The aim of this thesis was to study the biomarker homocysteine and other novel potential vascular risk factors for dementia. In an out-patient based study of a cohort of 926 consecutive subjects referred to our Memory Unit during 1996―2000, serum-folate was lower and total plasma homocysteine (tHcy) and serum methyl malonate were higher in subjects being prescribed with B12. READ MORE