Search for dissertations about: "vasoactive intestinal polypeptide"

Showing result 1 - 5 of 20 swedish dissertations containing the words vasoactive intestinal polypeptide.

  1. 1. Neuro-immuno-regulation of inflammation in the colonic mucosa : Focus on mast cells and eosinophils in bowel disorders

    Author : Maria Teresa Casado Bedmar; Åsa Keita; Johan D Söderholm; Marie Carlson; Melanie Gareau; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; Eosinophils; Vasoactive intestinal polypeptide; Neuro-immune; Intestinal barrier; Irritable bowel syndrome; Inflammatory bowel diseases; Ussing chamber; Advance image analysis;

    Abstract : Intestinal homeostasis is key to control uptake across the mucosa and protect from harmful substances. Disturbances in the bidirectional communication between the gut and the brain are implicated in irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD), being Crohn’s disease (CD) and ulcerative colitis (UC) the two most common IBD subtypes. READ MORE

  2. 2. Intestinal barrier function in health and disease

    Author : Pernilla Nejdfors; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; VIP.; PACAP; secretion; ion transport; urine reservoir; radiation therapy; ulcerative colitis; macromolecules; dextran; mannitol; Ussing chamber; Intestinal permeability; mucosa; Animal physiology; Djurfysiologi; Physiology; Fysiologi;

    Abstract : The intestinal epithelium has the dual function of absorbing nutrients and water as well as being a barrier to potentially harmful substances such as macromolecules and bacteria. In the present thesis the barrier function of the intestinal mucosa was studied in vitro in Ussing diffusion chambers. READ MORE

  3. 3. Aspects of aqueous humor dynamics : Studies in vivo and in vitro

    Author : Maria Samuelsson-Almén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Aqneous humor flow; intraocular pressure; adenylate cyclase; nonpigmented ciliary epithelium; pituitary adenylate cyclase-activating polypeptide; vasoactive intestinal polypeptide; dopamine; prostaglandin; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Abstract : The purpose of the present investigation was to study the effects of PGF2α-l-isopropylester, some neuropeptides, and pharmacological agents on aqueous humor dynamics and intraocular pressure (IOP) in vivo and on adenylate cyclase activity in the nonpigmented ciliary epithelium (NPE) in vitro.Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) caused a dose-dependent increase in cAMP formation, indicating that the NPE contains receptors for PACAP and VIP coupled to adenylate cyclase activation. READ MORE

  4. 4. The laryngeal mucosa and the superior laryngeal nerve of the rat : an immunohistochemical and electron microscopic study

    Author : Siw Domeij; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Superior laryngeal nerve; paraganglia; substance P; calcitonin gene-related peptide; neuropeptide Y; vasoactive intestinal polypeptide; enkephalin; mast cells; electron microscopy; immunohistochemistry;

    Abstract : Neuropeptides are present in nerve fibers of the upper and lower airways. Local release of these substances may be of importance for the pathophysiology of airway disorders and may play a role in responses to different stimuli. However, little is known about the distribution of neuropeptides in the larynx. READ MORE

  5. 5. An experimental study on the interaction between the neuro-endocrine and immune systems in the gastrointestinal tract

    Author : Bi-Feng Qian; Eva Ekblad; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastrointestinal tract; neuro-endocrine system; substance P; vasoactive intestinal polypeptide; vagus nerves; mucosal immune system; T lymphocytes; cytokines; inflammation; mouse;

    Abstract : The mucosa lining of the gastrointestinal (GI) tract is in immediate contact with food nutrients to allow a rapid and efficient digestion and absorption and at the same time protects against the incessant risk of attack from pathogenic microbes. Maintenance of normal physiological activities in the GI tract is dependent on a number of regulatory interactions between the nervous, endocrine, and immune systems, as well as environmental and genetic factors. READ MORE