Search for dissertations about: "verotoxin"

Found 5 swedish dissertations containing the word verotoxin.

2. 1. Carbohydrate-Based Inhibitors of Pathogen Adhesion to Cell Surface Glycoconjugates

   Author : Henrik C Hansen; Centrum för analys och syntes; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Galabiose analogs; Globotriose analogs; Escherichia coli; verotoxin; PapG adhesion; Streptococcus suis; Dendrimers; Multivalency; Amino-deoxy analogs; Organic chemistry; Inhibitor; Ceramide analogs; Glycoconjugates; Organisk kemi;

   Abstract : The fact that a growing number of pathogens develop resistance against traditional treatment is a growing medical problem. Infections, which until now have been harmless, might turn into life threatening diseases. These problems have led to an intensified search for alternative treatments. Analogs of cell surface glycoconjugates are an alternative. READ MORE

4. 2. Synthesis of Conformationally Restricted Oligosaccharides

   Author : Michael Wilstermann; Centrum för analys och syntes; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Streptococcus suis; E. coli; neoglycolipid; ganglioside-lactam; xylose; methylene acetal; sialic acid; Conformational Restriction; galabiose; Organic chemistry; Organisk kemi;

   Abstract : Gangliosides are sialic acid-containing glycosphingolipids that often are present in increased amounts on tumor cells. Since the gangliosides are hydroxy-acids, they can form lactones. The lactones have been suspected to be more immunogenic than the open forms, but are in practise poor immunogens due to their ease of hydrolysis. READ MORE

5. 3. Transmission and dynamics of VTEC O157:H7 : a story about the complex associations between pathogen, host and environment

   Author : Lena-Mari Tamminen; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Verotoxin-producing Escherichia coli serotype O157:H7 (VTEC O157:H7), is a zoonotic pathogen often transmitted from cattle to humans. In Sweden, domestic transmission of a highly virulent subtype of VTEC O157:H7, originating in regional clusters of infected cattle farms, is increasing. READ MORE

6. 4. Thermal treatment of organic waste and its function as a controlled risk mitigation strategy

   Author : Josefine Elving; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

   Abstract : Land application of organic waste is a convenient disposal method, improves soil properties by adding organic matter and recycles plant nutrients. Used in this way, organic waste is a resource, but it can also be a transmission route for pathogens with animal and human origin, such as Salmonella, verotoxin-producing Escherichia coli (VTEC) and avian influenza virus (AIV). READ MORE

7. 5. Targeting Gb3 and apoptosis-related proteins to overcome cisplatin resistance

   Author : Andreas Tyler; Kjell Grankvist; Simon Ekman; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cisplatin resistance; exosomes; gb3; HSP70; the Bcl-2 family; cell research; cellforskning; Medical Cell Biology; medicinsk cellbiologi; onkologi; Oncology;

   Abstract : Background Cisplatin is used for treatment of malignant pleural mesothelioma (MPM) and non-small cell lung cancer (NSCLC) but treatment with cisplatin often leads to acquired resistance to cisplatin, resulting in poor patient survival. Globotriaosylceramide (Gb3) and multidrug resistance protein 1 (MDR1) have been associated with cisplatin resistance. READ MORE