Search for dissertations about: "very low density lipoprotein VLDL"

Showing result 1 - 5 of 20 swedish dissertations containing the words very low density lipoprotein VLDL.

2. 1. Mechanisms for and consequences of cellular lipid accumulation - Role of the Very Low Density Lipoprotein (VLDL) receptor

   Author : Jeanna Perman; Göteborgs universitet; []
   Keywords : very low density lipoprotein receptor; lipid accumulation;

   Abstract : Lipid accumulation in non adipose tissue is associated with various cases of tissue dysfunction and tissue failure. Reduced availability of oxygen is known to cause intracellular lipid accumulation in cardiomyocytes as well as in hearts. READ MORE

4. 2. The assembly and secretion of ApoB containing lipoproteins

   Author : Pia Stillemark; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apolipoprotein B; lipoprotein; VLDL; microsomal triglyceride transfer protein; chaperone;

   Abstract : Increased levels of cholesterol and triglycerides in the blood are important risk factors for the development of premature atherosclerosis and its complications such as coronary-heart diseases, stroke and peripheral vascular diseases. These diseases are the major causes of death in Europe, USA and part of Asia. READ MORE

5. 3. Lipid storage and secretion. Studies on VLDL assembly and foam cell formation

   Author : Björn Magnusson; Göteborgs universitet; []
   Keywords : ADP-ribosylation factor 1; very low density lipoprotein; lipid droplet; adipocyte differentiation-related protein; hypoxia; foam cell;

   Abstract : This thesis deals with formation of two factors of upmost importance for the development of atherosclerosis: the triglyceride rich very low density lipoproteins 1 (VLDL1) and the lipid loaded macrophages ("foam cells"- characteristic features of the atherosclerotic lesion). Both these processes depend on the cellular accumulation of lipids. READ MORE

6. 4. Macrophage Activation and AP-1 in Atherosclerosis

   Author : Maria Stollenwerk; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Proteins; enzymology; Proteiner; enzymologi; Cardiovascular system; carotid plaque; interleukin-1b; caspase-1.; very low-density lipoprotein; fatty acids; activator protein-1; inflammation; Atherosclerosis; nuclear factor-kB; macrophages; tumor necrosis factor;

   Abstract : High levels of very low density lipoprotein (VLDL) and intermediate density lipoprotein (IDL) have been identified as independent risk factors for coronary heart disease. Hypertriglyceridemia is generally associated with an increased expression of inflammatory makers and inflammation is thought to contribute to atherosclerosis and its complications. READ MORE

7. 5. Studies on the atherogenicity of apoB-containing lipoproteins in type 2 diabetes

   Author : Camilla Pettersson; Göteborgs universitet; []
   Keywords : Type 2 diabetes; metabolic syndrome; atherosclerosis; VLDL; LDL; secretory phospholipase A2 group V; inflammation; complement; apolipoprotein; lysozyme;

   Abstract : Type 2 diabetes (T2D) and the metabolic syndrome (MetS), two conditions that are rapidly increasing in prevalence, as well as the dyslipoproteinemia and subclinical inflammation characteristic for these conditions, are associated with an increased risk for developing and dying of cardiovascular disease (CVD). The aim of this thesis was to investigate possible atherogenic properties of very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) in T2D and MetS. READ MORE