Search for dissertations about: "very low-density lipoprotein"

Showing result 16 - 20 of 34 swedish dissertations containing the words very low-density lipoprotein.

  2. 16. Studies on the atherogenicity of apoB-containing lipoproteins in type 2 diabetes

    Author : Camilla Pettersson; Göteborgs universitet; []
    Keywords : Type 2 diabetes; metabolic syndrome; atherosclerosis; VLDL; LDL; secretory phospholipase A2 group V; inflammation; complement; apolipoprotein; lysozyme;

    Abstract : Type 2 diabetes (T2D) and the metabolic syndrome (MetS), two conditions that are rapidly increasing in prevalence, as well as the dyslipoproteinemia and subclinical inflammation characteristic for these conditions, are associated with an increased risk for developing and dying of cardiovascular disease (CVD). The aim of this thesis was to investigate possible atherogenic properties of very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) in T2D and MetS. READ MORE

  4. 17. T-cell specificity and regulation in atherosclerosis

    Author : Anton Gisterå; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases is atherosclerosis, a chronic inflammatory disease. Subendothelial retention of lipoproteins triggers monocyte-derived macrophages and T-helper (Th) 1 cells to form lipid-laden atherosclerotic plaques in the artery wall. READ MORE

  5. 18. Fatty acids induce potentially atherogenic changes in extracellular matrix proteoglycans

    Author : Mariam Rodríguez-Lee; Göteborgs universitet; []
    Keywords : proteoglycans; glycosaminoglycans; fatty acids; smooth muscle cells; hepatocytes; LDL binding; remnant clearance; insulin resistance; type 2 diabetes;

    Abstract : Insulin resistance and type 2 diabetes (T2D) are associated with an increased prevalence of atherosclerotic cardiovascular disease (CVD). A key step in the initiation of atherogenesis is retention of low density lipoproteins (LDL) in the intima by chondroitin sulfate (CS)-rich proteoglycans (PG). READ MORE

  6. 19. Pharmacometric Characterization of Postprandial Responses and Taste Perception in Individuals with Obesity

    Author : Jennifer Leohr; Maria Kjellsson; Andrew Hooker; Martin Adiels; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; mechanism-based; categorical modeling; obesity; triglycerides; glucose homeostasis; taste perception; linked categorical;

    Abstract : Obesity is a major health epidemic worldwide and occurs when long-term excess of energy intake beyond energy utilization leads to an increase in adipose tissue. Energy balance is coordinated by the central nervous system regulation of appetite and adaptive thermogenesis via a complex array of neuropeptides which communicate to the periphery by various circulating measures dictating the utilization of various energy sources such as, carbohydrates, fat, or protein. READ MORE

  7. 20. A role of CD44 in atherosclerosis? Studies in mice and humans

    Author : Sara Sjöberg; Göteborgs universitet; []
    Keywords : CD44; atherosclerosis; interleukin-6; T cell; mast cell;

    Abstract : Atherosclerosis is an inflammatory disease that can lead to clinical complications such as myocardial infarction and stroke. Expressed in both vascular and inflammatory cells, adhesion molecule CD44 can be cleaved from the cell surface, and soluble CD44 can be detected in blood. READ MORE