Search for dissertations about: "very low-density lipoprotein"

Showing result 6 - 10 of 34 swedish dissertations containing the words very low-density lipoprotein.

  2. 6. Lipid storage and secretion. Studies on VLDL assembly and foam cell formation

    Author : Björn Magnusson; Göteborgs universitet; []
    Keywords : ADP-ribosylation factor 1; very low density lipoprotein; lipid droplet; adipocyte differentiation-related protein; hypoxia; foam cell;

    Abstract : This thesis deals with formation of two factors of upmost importance for the development of atherosclerosis: the triglyceride rich very low density lipoproteins 1 (VLDL1) and the lipid loaded macrophages ("foam cells"- characteristic features of the atherosclerotic lesion). Both these processes depend on the cellular accumulation of lipids. READ MORE

  4. 7. Studies on lipoprotein metabolism and atherogenesis

    Author : Katharina Slätis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ApoA1; ApoB; ApoE; atherosclerosis; bile acids; cholic acid; cholesterol; cholesterol absorption; CYP7A1; CYP8B1; dexamethasone; GC-1; PAI-1; thyroid hormone receptor; very low density lipoprotein receptor;

    Abstract : Atherosclerosis is the primary cause of cardiovascular events such as angina pectoris and myocardial infarction, which together with stroke are responsible for around 50% of all deaths in the United States and Europe. Usually atherosclerosis develops over several decades and leads to a progressive narrowing of arterial vessels. READ MORE

  5. 8. The assembly and secretion of ApoB containing lipoproteins

    Author : Pia Stillemark; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apolipoprotein B; lipoprotein; VLDL; microsomal triglyceride transfer protein; chaperone;

    Abstract : Increased levels of cholesterol and triglycerides in the blood are important risk factors for the development of premature atherosclerosis and its complications such as coronary-heart diseases, stroke and peripheral vascular diseases. These diseases are the major causes of death in Europe, USA and part of Asia. READ MORE

  6. 9. Lipoproteins in the postprandial state: Studies on the metabolism of triglyceride-rich lipoproteins using multicompartmental models

    Author : Elias Björnson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipoprotein metabolism; Atherosclerotic cardiovascular disease;

    Abstract : Lipoproteins are lipid-containing spherical particles that circulate in the human blood stream. The reason for their intense study over the decades is their ability to cause atherosclerosis1. READ MORE

  7. 10. The regulation of blood coagulation by high-density lipoprotein particles

    Author : Cecilia Oslakovic; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : High-density lipoprotein (HDL) has anti-atherogenic properties and the plasma level of HDL cholesterol correlates inversely with the risk of coronary artery disease. The atheroprotective functions of HDL can be explained by its function in the reverse cholesterol transport. READ MORE