Search for dissertations about: "vesicle trafficking"

Showing result 1 - 5 of 30 swedish dissertations containing the words vesicle trafficking.

  2. 1. Exploring Cellular Dynamics : From Vesicle Tethering to Cell Migration

    Author : Parham Ashrafzadeh; Johan Kreuger; Jonas Fuxe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; cancer; cell migration; exocyst complex; exocytosis; FGD5; lipid rafts; plasma membrane; receptor trafficking; VEGFR2;

    Abstract : Cells in the body communicate with each other in order to cooperate efficiently. This communication is in part achieved by regulated secretion of signaling molecules, which when released from a cell may activate receptors present at the plasma membrane of an adjacent cell. Such signals affect both cell fate and behavior. READ MORE

  4. 2. Proteostasis beyond chaperones - Auxiliary systems in the management of damaged proteins

    Author : Rebecca Josefson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; aging; proteostasis; protein quality control; asymmetric inheritance; vesicle trafficking;

    Abstract : Aging entails loss of functionality and increased risk of death, even for unicellular organisms, such as the yeast Saccharomyces cerevisiae. On a cellular level, aging is accompanied by an accumulation of harmful aging factors, e.g. damaged and aggregated proteins. READ MORE

  5. 3. Components controlling vesicle trafficking and regulated exocytosis in pancreatic beta-cells

    Author : Slavena Andrea Mandic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Regulated exocytosis is a sophisticated, well-organized and conserved multistage process underlying release of both neurotransmitters and hormones. Exocytosis is mediated by SNARE proteins that act at the center stage by forming a SNARE complex with the intrinsic capability to execute membrane fusion. READ MORE

  6. 4. Membrane Stress and the Role of GYF Domain Proteins

    Author : Alexander Georgiev; Åke Wieslander; Hana Sychrova; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; SYH1; SMY2; YPT6; RIC1; MYR1; processing bodies; vesicular trafficking; lipid bilayer; budding yeast; GYF; membrane stress; mRNA decay; Saccharomyces cerevisiae; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : Intracellular membrane trafficking is regulated by a large number of protein complexes and lipids. Blocking of trafficking disrupts normal membrane dynamics and causes membrane stress. READ MORE

  7. 5. Organization of signaling networks during receptor-mediated membrane protein trafficking

    Author : Zongpei Chen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The mechanisms by which receptor signals are organized in a synergic/hierarchical manner in time and space during regulation of integral membrane protein traffic remain a present challenge. The aim of this study was to address some critical aspects of these processes. READ MORE