Search for dissertations about: "vinylaziridines"
Found 3 swedish dissertations containing the word vinylaziridines.
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1. A Regio- and Stereodivergent Route to All Isomers of vic-Amino Alcohols
Abstract : The first part of this thesis describes a synthetic strategythat provides all eight possible isomers of a given vic-aminoalcohol starting from vinylepoxides. The value of a generalroute is evident, as several isomers are needed ininvestigations of structure-activity relationships forpharmacologically active derivatives, and for optimizing theperformance of chiral ligands containing the amino alcoholmoiety. READ MORE
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2. Synthesis and [3,3]-Sigmatropic Rearrangement of Vinylaziridines
Abstract : A general synthetic route from vinylepoxides to vinylaziridines via 1,2-amino alcohols was developed. The 1,2-amino alcohols were obtained from a stereospecific and regioselective aminolysis of vinylepoxides. The synthetic scope of the aminolysis could be expanded by the use of a microwave-assisted protocol. READ MORE
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3. New Methodologies in Organic Chemistry: Applications to the Synthesis of α-Amino Acids and Natural Products
Abstract : This thesis deals with the development and application of new synthetic methodology in organic chemistry. The first part describes the development of a new protocol for the synthesis of 3-pyrrolines by means of a microwave-assisted ring-expansion reaction of 2-vinylaziridines. READ MORE