Search for dissertations about: "viral hepatitis"

Showing result 1 - 5 of 78 swedish dissertations containing the words viral hepatitis.

  1. 1. Hepatitis C virus. Aspects on natural history, antibody response, and viral quantification

    Author : Martin Lagging; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Hepatitis C virus; nosocomial infection; pseudotyped virus; fibrosis; viral quantification;

    Abstract : Hepatitis C virus (HCV) is the major cause of parenterally transmitted non-A, non-B hepatitis, and is associated with chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Despite the screening of blood products nosocomial spread of HCV continues to occur. READ MORE

  2. 2. Novel Procedures for Identification and Characterization of Viral Proteases Inhibitors

    Author : Angelica Ehrenberg; Helena Danielson; Celia Schiffer; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; drug discovery; viral proteases; inhibitors; Hepatitis C; NS3; cytomegalovirus; Biokemi; Biochemistry;

    Abstract : Viral proteases are often considered to be attractive drug targets because of their crucial function in the viral replication machinery. In order to increase our knowledge of these important targets and to contribute to the discovery and development of new antiviral drugs, the proteases from hepatitis C virus (HCV) and human cytomegalovirus (HCMV) have been produced and their interactions with inhibitors and fragments have been characterized, using enzyme inhibition and SPR biosensor based interaction assay. READ MORE

  3. 3. Viral and host determinants in hepatitis B

    Author : Hossein Sendi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : The outcome of hepatitis B infection is highly variable, ranging from acute disease resulting in the elimination of infection to persistent infection that can lead to cirrhosis or hepatocellular carcinoma. The factors determining the outcome in an individual are not fully known but may be classified into viral and host factors. READ MORE

  4. 4. Hepatitis C virus infection. Viral genotypes and factors promoting liver fibrosis

    Author : Johan Westin; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C virus; genotypes; epidemiology; liver fibrosis; histology; scoring; prognosis; alcohol; liver steatosis;

    Abstract : Hepatitis C virus (HCV) is associated with chronic infection in a majority of infected individuals. Chronic hepatitis C may result in liver cirrhosis or hepatocellular cancer and is therefore considered a major health problem worldwide. READ MORE

  5. 5. Hepatitis B virus replication and integration

    Author : Simon B. Larsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; hepatitis B virus; replication; integration; HBV DNA; HBsAg;

    Abstract : Chronic infection with hepatitis B virus (HBV) affects 240 million people worldwide and may cause liver disease including hepatocellular carcinoma (HCC). Initially patients have high levels of HBV DNA in their blood, no liver disease and express the e antigen (HBeAg). READ MORE