Search for dissertations about: "viral hepatitis"

Showing result 36 - 40 of 90 swedish dissertations containing the words viral hepatitis.

  2. 36. Ribavirin : dose and concentration in treatment of chronic hepatitis C infected patients

    Author : Karin Lindahl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Hepatits C; ribavirin; pharmacokinetics; renal function; plasma concentration; anaemia; population pharmacokinetic analysis; peginterferon; sustained viral response;

    Abstract : Chronic hepatitis C infection is a global health problem with 170 million patients infected. Hepatitis C virus (HCV) infection is a leading cause of end stage liver disease. Current antiviral treatment options available are not optimal either regarding cure of disease or risk of side effects. READ MORE

  4. 37. Protein interactions involved in viral replication characterized by T7 phage display

    Author : Hamid Houshmand; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; protein-protein interaktion; fagdisplayteknik; HCV; polyomavirus; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Abstract : Protein interactions are essential for many cellular processes. By utilizing protein-protein interactions, viruses can infect their host cells and replicate. Phage display can be used for identification and characterization of protein-protein interactions. READ MORE

  5. 38. Potential role of MAIT cells in cancer immunotherapy and viral infection

    Author : Katie Healy; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mucosa-associated invariant T (MAIT) cells are an unconventional T cell subset with specialized antimicrobial functions. In humans, MAIT cells are characterized by their effector memory phenotype, rapid cytolytic capacity, and tissue-homing properties. READ MORE

  6. 39. Hepatitis B virus infection and genomic changes from a long-term perspective

    Author : Jonas Bläckberg; Sektion III; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infektioner; Infections; cor promoter; precore; occult infection; HBV; mutation;

    Abstract : Hepatitis B virus is a non-cytopathic virus with a small, circular, partially double-stranded DNA of 3.2 kb. It causes acute and chronic inflammatory liver disease and hepatocellular carcinoma (HCC). Retesting of stored sera from an outbreak of acute hepatitis in 1969-72 allowed identification of 126 cases of acute hepatitis B. READ MORE

  7. 40. Development of vaccines and experimental models for chronic infections caused by the hepatitis C virus

    Author : Lars Frelin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HCV; chronic infection; DNA vaccine; NS3; viral vectors; transgenic mice;

    Abstract : The hepatitis C virus (HCV) is a major cause of chronic liver disease worldwide. It is estimated that HCV affects approximately 170 million people around the world. One feature of HCV infection is the high rate of viral persistence. READ MORE