Search for dissertations about: "viral quantification"

Showing result 6 - 10 of 33 swedish dissertations containing the words viral quantification.

  2. 6. On HIV-1 latency and viral reservoirs

    Author : Tomas Mellberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; Latency; Intravenous immunoglobulin; residual viremia; low level viremia; Ultrasensitive PCR methods; Central nervous system;

    Abstract : HIV-1 establishes a latent infection that is inaccessible to treatment in cellular and anatomical reservoirs. This thesis concerns several problematic issues of HIV-1 persistence, including ways to measure and monitor both the virus at low viral concentrations and the depletion of the reservoir. READ MORE

  4. 7. Evaluation of reverse transcriptase assay for viral load monitoring

    Author : Gary E Corrigan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Retaining an active reverse transcriptase (RT) enzyme is a fundamental requirement for all retroviruses to replicate. Bearing in mind that HIV has a very high propensity to mutate measuring RT activity to determine the level of retroviral replication has the capacity to eliminate problems associated with divergence, as the virus at all costs must retain an active RT enzyme. READ MORE

  5. 8. Human Papillomavirus Load and Cervical Carcinoma

    Author : Martin Moberg; Ulf Gyllensten; Björn Hagmar; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; cervical cancer; human papillomavirus; viral load; HLA class II; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Human Papillomavirus (HPV) is a key factor in the development of cervical cancer. Out of the more than 100 known HPV types 13 are considered oncogenic. In addition to presence of the virus several other factors have been proposed to influence risk of cervical cancer. READ MORE

  6. 9. Nucleic acid analysis tools : Novel technologies and biomedical applications

    Author : Iván Hernández-Neuta; Mats Nilsson; Frank Bier; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nucleic acid analysis; padlock probes; selector probes; rolling circle amplification; microfluidics; single-molecule detection; digital quantification; fluorescence microscopy; mobile phone microscopy; molecular diagnostics; virology; Biochemistry; biokemi;

    Abstract : Nucleic acids are fundamental molecules of living organisms functioning essentially as the molecular information carriers of life. From how an organism is built to how it responds to external conditions, all of it, can be found in the form of nucleic acid sequences inside every single cell of every life form on earth. READ MORE

  7. 10. Improved methodologies for molecular detection and quantification of viruses in food

    Author : Sofia Persson; Patrik Ellström; Magnus Simonsson; Wim van der Poel; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; foodborne virus; digital PCR; real-time PCR; validation; assay design; food safety; Medicinsk vetenskap; Medical Science;

    Abstract : Foodborne viruses such as norovirus, hepatitis A virus and hepatitis E virus cause a high burden of disease worldwide. Reverse transcription (RT) quantitative real-time PCR (qPCR) is the current standard method for monitoring viral contamination in the food chain. READ MORE