Search for dissertations about: "viral"

Showing result 1 - 5 of 1026 swedish dissertations containing the word viral.

  1. 1. Bovine viral diarrhea virus : methods for purification of the virus and the viral subunits

    Author : Per Kårsnäs; Uppsala universitet; []

    Abstract : .... READ MORE

  2. 2. HIV Persistence and Viral Reservoirs

    Author : Arvid Edén; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; antiretroviral therapy; latency; cerebrospinal fluid; central nervous system; efavirenz; lopinavir; atazanavir; neopterin; viral decay;

    Abstract : Although antiretroviral therapy (ART) can effectively inhibit replication of human immunodeficiency virus type 1 (HIV-1), the virus is able to persist in cellular and anatomical viral reservoirs. Latently infected resting memory CD4+ T-cells are an important cellular reservoir, and the central nervous system (CNS) an important anatomical reservoir for HIV-1 infection. READ MORE

  3. 3. Evolution and viral mimicry of short linear motif-mediated interactions

    Author : Filip Mihalič; Per Jemth; Leo James; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; phage display; protein-protein interactions; large-scale discovery; short linear motifs; viral mimcry; viral hijacking; Biokemi; Biochemistry; Medical Biochemistry; Medicinsk biokemi;

    Abstract : Proteins are one of the most fundamental building blocks of life and their interactions regulate every cellular process. Historically they have been conceptualized as predominantly folded entities with well-defined secondary and tertiary structures. READ MORE

  4. 4. On gastrointestinal viral infections

    Author : Thomas Beck-Friis; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; norovirus; rotavirus; SARS-CoV-2; gastroenteritis; diagnosis; elderly; epidemiology; humidity; COVID-19; genomic structural variation;

    Abstract : Gastrointestinal viral infections cause considerable morbidity and mortality worldwide. Many factors influencing clinical presentation, disease severity, epidemiology, and transmission are not fully understood. READ MORE

  5. 5. Interaction Characteristics of Viral Protease Targets and Inhibitors : Perspectives for drug discovery and development of model systems

    Author : Cynthia F Shuman; Jordan J N Tang; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; viral proteases; biomolecular interactions; kinetics; thermodynamics; biosensors; drug discovery; Biokemi; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Abstract : Viral proteases are important targets for anti-viral drugs. Discovery of protease inhibitors as anti-viral drugs is aided by an understanding of the interactions between viral protease and inhibitors. This thesis addresses the characterization of protease-inhibitor interactions for application to drug discovery and model system development. READ MORE