Search for dissertations about: "virulence"

Showing result 21 - 25 of 462 swedish dissertations containing the word virulence.

  2. 21. Virulence determinants of the insect pathogen Bacillus thuringiensis; : Molecular characterization of flagellins and the virulence protease immune inhibitor A

    Author : Ann Lövgren; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mikrobiologi; Microbiology;

    Abstract : Bacillus thuringiensis (Bt) is a motile, Gram positive, rod-shaped and spore-forminginsect pathogenic bacterium found on plants and in soil. The main insecticidal activityresides in a proteinacious crystal inclusion body (the S-endotoxin), but also the sporesare important for lethality. READ MORE

  4. 22. The Colonization Strategies of Nontypeable Haemophilus influenzae - Bacterial Colonization Factors and Vaccine Development

    Author : Farshid Jalalvand; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ABC-transporter; bacterial colonization; Haemophilus influenzae; Haemophilus Protein F; laminin; NTHi; pathogenesis; vaccine; virulence; vitronectin.;

    Abstract : Nontypeable Haemophilus influenzae (NTHi) is a remarkably proficient colonizer of the human respiratory tract. The aim of this thesis has been to characterize currently known, and identify novel, bacterial factors involved in the key processes of colonization and pathogenesis, namely adherence to host tissue and evasion of the host innate immunity. READ MORE

  5. 23. Studies on cell wall-attached proteins of Streptococcus pyogenes

    Author : Magnus Rasmussen; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insertion sequence; phase variation; collagen-like; alpha2-macroglobulin; pattern; virulence; surface protein; Stretococcus pyogenes; cell wall-attached protein; Clinical biology; Klinisk biologi;

    Abstract : Cell wall-attached proteins (CWPs) are important for the virulence of Gram-positive bacteria, but are also targets for the host immune system. CWPs have a conserved COOH-terminal region, responsible for cell wall-sorting. A pattern based on this conserved region was developed. READ MORE

  6. 24. Role of the Yersinia protein YopK in microbe-host interactions

    Author : Sara Thorslund; Maria Fällman; James Bliska; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia; YopK; T3SS; antiphagocytosis; neutrophil; translocation; virulence; molekylärbiologi; Molecular Biology;

    Abstract : There are three human pathogenic species of the genus Yersiniae: Yersinia pestis, Yersinia enterocolitica, and Yersinia pseudotuberculosis. To cause disease, these strains inhibit several key innate defense mechanisms, including phagocytosis, the critical process for bacterial clearance. READ MORE

  7. 25. Multiple functions of YopN in the Yersinia pseudotuberculosis type III secretion system : from regulation to in vivo infection

    Author : Sarp Bamyaci; Åke Forsberg; Edouard Galyov; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Type III secretion system; Yersinia; YopN; virulence; phagocytosis; mouse infection; secretion kinetics;

    Abstract : The type 3 secretion systems (T3SSs) are virulence mechanisms used by various Gram-negative bacteria to overcome the host immunity. They are often target-cell contact induced and activated. Activation results in targeting of virulence effector substrates into host cells. READ MORE