Search for dissertations about: "virus purification"

Showing result 21 - 25 of 37 swedish dissertations containing the words virus purification.

  2. 21. Modeling Antibody Aggregation in Downstream Processing

    Author : Frida Ojala; Avdelningen för kemiteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Antibody; Aggregation; Downstream processing; Size exclusion chromatography; Reversible reaction model; General rate model;

    Abstract : Antibodies are part of the immune system where their purpose is to recognize and neutralize foreign species such as viruses and bacteria, thus preventing and curing infections. The trend of using antibodies in the treatment of, for example, cancer is increasing. READ MORE

  4. 22. Structural and biochemical studies of phage P2 DNA-binding proteins and human tetraspanins

    Author : Karin Skaar; Martin Högbom; Simon Newstead; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Abstract : Biochemical studies of proteins are crucial for a more detailed view of the world around us. The focus of biochemical studies can vary, from a complex mammalian system to a more simple viral entity, but the same methods and principles apply. In biochemistry one rely on both in vitro and in vivo analyses to understand biological processes. READ MORE

  5. 23. Viperin, a multifunctional radical SAM enzyme : biogenesis and antiviral mechanisms

    Author : Arunkumar Upadhyay; Anna K. Överby; Niklas Arnberg; Richard Lundmark; Michael Beard; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Viperin (virus-inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is an interferon-induced antiviral protein. It has three distinct functional domains: the N-terminal domain, the radical SAM (S-adenosylmethionine) domain for binding iron-sulphur cluster, and the C-terminus domain. READ MORE

  6. 24. Fetal hematopoietic cells in early gestation : aspects in view of fetal transplantation

    Author : Sverker Ek; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Fetal stem cells; fetal liver; fetal hematopoiesis; immunological ontogeny; fetal transplantation; cytokines; CD34 enrichment;

    Abstract : The fetus as a patient is a challenge. There are opportunities for early, sometimes life-saving procedures or there may be advantages in prenatal rather than postnatal intervention. This is the case in fetal hematopoietic cell (FHC) transplantation where conditions caused by a defect in blood cell formation may be life-threatening to the fetus. READ MORE

  7. 25. HIV-1 reverse transcriptase activity assays based on monoclonal antibodies to native enzyme : Applications on studies of antiviral substances and immunological variation of reverse transcriptase

    Author : Ann-Sofie Rytting; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; HIV-1; reverse transcriptase; monoclonal antibody; activity assay; subtype; RT inhibitor; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Abstract : Specific detection of HIV-1 reverse transcriptase (RT) activity in crude materials was enhanced using a capture assay for immunopurification and subsequent activity assay. The purification step was achieved by anti-HIV-1 RT monoclonal antibodies (Mabs) immobilized onto a solid carrier. READ MORE