Search for dissertations about: "visceral mesoderm"

Showing result 1 - 5 of 7 swedish dissertations containing the words visceral mesoderm.

  2. 1. Midgut and muscle development in Drosophila melanogaster

    Author : Margret Shirinian; Ruth Palmer; Anne Uve; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drosophila; visceral mesoderm; endoderm; somatic muscles; Alk; C3G; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The fully developed and functional Drosophila midgut comprises two layers, the visceral mesoderm and the endoderm. The visceral muscle of the midgut is formed by the fusion of founder cells with fusion competent cells to form the muscle syncytia. READ MORE

  4. 2. Deciphering the Alk signaling pathway in Drosophila

    Author : Fredrik Hugosson; Ruth H. Palmer; Osamu Shimmi; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Alk; RTK; visceral mesoderm; signal transduction; growth factor; transcription factor; molekylärbiologi; Molecular Biology;

    Abstract : In Drosophila melanogaster the visceral mesoderm (VM) develops during embryogenesis in a process where myoblasts become specified to generate two distinct cell types, the founder cells (FCs) and the fusion competent myoblasts (FCMs) that consequently fuses. The cell specification is dependent on cell signaling mediated by the receptor tyrosine kinase (RTK) Anaplastic lymphoma kinase (Alk) and its ligand Jelly belly (Jeb), how this further sets up different identity programs that drive myoblasts to differentiate into FCs and FCMs is still not well understood. READ MORE

  5. 3. Harnessing the power of model systems to investigate regulation of Anaplastic Lymphoma Kinase function

    Author : Patricia Mendoza-Garcia; Ruth Palmer; Jan Larsson; Åsa Rasmuson Lestander; Stefan Luschnig; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RTK; ALK; Drosophila; Danio rerio; ALKALs; signal transduction; transcription factor; visceral mesoderm; iridophores; neural crest; molekylärbiologi; Molecular Biology;

    Abstract : The anaplastic lymphoma kinase (ALK), initially identified as a translocation partner in anaplastic large cell lymphoma (ALCL), has been described in a number of tumors such as neuroblastoma. Neuroblastoma is a neural crest derived malignancy of the sympathetic nervous system. READ MORE

  6. 4. Identification of downstream targets of Alk signaling in Drosophila melanogaster

    Author : Gaurav Varshney; Ruth Palmer; Udo Hacker; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Alk; Jeb; visceral muscles; somatic muscles; Delilah; Goliath; Hand; Molecular biology; Molekylärbiologi;

    Abstract : The Drosophila gene Anaplastic lymphoma kinase (Alk) is homologous to mammalian ALK, a member of the Alk/Ltk family of receptor tyrosine kinases. In Drosophila Alk is crucial for development of the embryonic visceral mesoderm, where it is the receptor for Jelly Belly (Jeb) ligand. READ MORE

  7. 5. Investigating the function of the Receptor Tyrosine Kinase ALK during Drosophila melanogaster development

    Author : Christina Lorén; Mike Taylor; Umeå universitet; []
    Keywords : DAlk; receptor tyrosine kinase; Jeb; visceral muscle fusion; ERK; Drosophila; endoderm; molecular cell biology; molekylär cellbiologi;

    Abstract : The Drosophila melanogaster gene Anaplastic Lymphoma Kinase (DAlk) is homologous to mammalian Alk, which is a member of the Alk/Ltk family of receptor tyrosine kinases (RTKs). In humans the t(2;5) translocation involving the Alk locus encodes an active form of Alk that is the causative agent in Non-Hodgkin’s Lymphoma (Morris et al., 1994). READ MORE