Search for dissertations about: "vitamin a in psoriasis"

Showing result 1 - 5 of 7 swedish dissertations containing the words vitamin a in psoriasis.

  2. 1. Studies on Vitamin A Signaling in Psoriasis : A Comparison Between Normal and Lesional Keratinocytes

    Author : Teresa Karlsson; Jan Öivind Moskaug; Uppsala universitet; []
    Keywords : Medical sciences; Psoriasis; vitamin A; retinoids; retinoid receptor; differentiation; keratinocyte; skin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Dermatology and Venerology; dermatologi och venereologi;

    Abstract : Vitamin A and metabolites (retinoids) are crucial for normal epidermal maturation. Physiological effects are mediated by retinoic acid (RA) that activates nuclear retinoic acid receptors (RARs) in complexes with retinoid X receptors (RXRs), resulting in altered gene transcription.Psoriasis is a common disease with unknown etiology. READ MORE

  4. 2. Vitamin D and Vitamin D-binding Protein in Psoriasis and Effects of Treatment

    Author : Maria Siekkeri Vandikas; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; psoriasis; vitamin D; vitamin D-binding protein; phototherapy; tumor necrosis factor α inhibitor;

    Abstract : Background: Topical vitamin D analogues constitute an established treatment for psoriasis but the role of vitamin D in the pathogenesis of the disease remains controversial. The in loco production and immunomodulatory effects of vitamin D need to be elucidated. READ MORE

  5. 3. Vitamin D status in psoriasis patients treated with UVB therapy

    Author : Amra Osmancevic; Göteborgs universitet; []
    Keywords : Vitamin D; PTH; psoriasis; bone mineral density; ultraviolet UVB;

    Abstract : Vitamin D status in psoriasis patients treated with UVB therapy Amra Osmancevic Department of Dermatology and Venereology, Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden Abstract The thesis deals with the effect of ultraviolet B (UVB) 280-320 nm on vitamin D production in psoriasis patients during treatment with phototherapy. Background: Psoriasis is a chronic, inflammatory disease affecting the skin and potentially the joints. READ MORE

  6. 4. Catalytic Properties and Tissue Distribution of Cytochrome P450 4F8 and 4F12 : Expression of CYP4F8 in Eye Tissues and Psoriatic Lesions

    Author : Katarina Stark; Ernst H Oliw; Leif Bertilsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical pharmacology; Arachidonic acid metabolism; Cytochrome P450; 19-Hydroxyprostaglandins; Immunohistochemistry; Ocular tissues; Psoriasis; Farmaceutisk farmakologi; Pharmaceutical pharmacology; Farmaceutisk farmakologi;

    Abstract : The human cytochrome P450 (CYP) family of monooxygenases is important for metabolism of drugs and endogenous compounds, e.g., vitamin A and D, cholesterol, steroids, fatty acids, and eicosanoids. This thesis describes the tissue distribution, catalytic properties, and possible function of CYP4F8 and CYP4F12. READ MORE

  7. 5. Study of pruritus in psoriasis vulgaris : role of tachykinins

    Author : Beni Amatya; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Itch; pruritus; psoriasis; tachykinin; questionnaire; focus group; intradermal injection;

    Abstract : Pruritus has not been considered as the most important symptom of psoriasis. In the present thesis various methodologies have been used to investigate this symptom in psoriasis. The focus groups created a proper atmosphere for discussion on different aspects of pruritus in psoriasis. Pruritus was most common on the lower back and legs. READ MORE