Search for dissertations about: "voltage-dependent calcium channels"

Showing result 6 - 10 of 15 swedish dissertations containing the words voltage-dependent calcium channels.

2. 6. Regulation of the myogenic response and stretch-induced calcium signaling in the vascular wall: Novel insights into the role of microRNAs and protein tyrosine kinase 2

   Author : Anirban Bhattachariya; Kärlfysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; portal vein; resistance artery; myogenic tone; PYK2; calcium; microRNA;

   Abstract : Intraluminal pressure has a significant impact on vascular adaptability, phenotype and regulation of blood flow and pressure. On one hand, increased pressure/stretch for a prolonged time can cause structural changes in vessel wall; on the other hand, lack of pressure/stretch can promote a phenotype shift. READ MORE

4. 7. Ion channels and electrical activity in vascular smooth muscle: Effects of calcium store depletion, cholesterol and cholesterol-lowering drugs

   Author : Andreas Bergdahl; Kärlfysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; statins; endothelin; cholesterol; caveolae; smooth muscle; TRP; Ca2 channels; SOC;

   Abstract : Smooth muscle cells (SMCs) in the vessel wall contract to regulate blood flow and pressure, a function essential for normal circulation through tissues. On the other hand, migration and proliferation of SMCs are important factors in vascular disease, such as atherosclerosis and restenosis following surgical dilatation. READ MORE

5. 8. Investigation on Pre- and Postsynaptic Ca2+ Signaling in Neuronal Model Systems

   Author : Jelena Krjukova; Åkerman Karl; Kukkonen Jyrki; Rydqvist Bo; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; calcium; neurotransmitter release; nicotine; depolarization; G-protein coupled receptor; muscarinic; phospholipase C; m-3M3FBS; Fysiologi; Physiology; Fysiologi;

   Abstract : Communication between neuronal and non-neuronal is called volume transmission when the released neurotransmitter (NT) acts via diffusion and affects several target cells. Both the neurosecretory and postsynaptic cell responses are linked to [Ca2+]i elevations. READ MORE

6. 9. Calcium signaling : molecular mechanisms and cellular consequences

   Author : Seth Malmersjö; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Cells exploit calcium (Ca2+) signaling to transmit information. In a multicellular organism, each cell must be able recognize, process, and respond to information received from the surrounding environment. In this thesis I investigate molecular mechanisms and cellular consequences of Ca2+ signaling. READ MORE

7. 10. Ion channels and intrinsic membrane properties of locomotor network neurons in the lamprey spinal cord

   Author : Di Wang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Ion channels; calcium activated non-selective cation current ICAN ; L-type LVA calcium channels Cav 1.3 ; calcium channels; calcium imaging; NMDA; postinhibitory rebound PIR ; lamprey; central pattern generator CPG ; locomotion;

   Abstract : NMDA-receptor dependent membrane potential oscillations and postinhibitory rebound are examples of intrinsic membrane properties of many neurons of rhythm-generating networks, and are considered to play major roles in the operation of the spinal locomotor network of the lamprey vertebrate model. A significant feature of many lamprey spinal cord neurons is their ability to generate pacemaker-like membrane potential oscillations in the presence of the glutamate agonist NMDA. READ MORE