Search for dissertations about: "von Willebrand factor antigen"

Showing result 1 - 5 of 12 swedish dissertations containing the words von Willebrand factor antigen.

2. 1. Prognostic markers in prostate cancer : studies of a watchful waiting cohort with long follow up

   Author : Andreas Josefsson; Anders Bergh; Pernilla Wikström; Pär Stattin; Anders Bjartell; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Immunohistochemistry; Prognostic markers; biomarkers; Survival analysis; human; pathology; watchful waiting; tissue micro array; Endoglin; von willebrandt factor; ki67; ki-67; hyaluronan; patologi; Pathology;

   Abstract : Background: Prostate Cancer (PC) is a common and highly variable disease. Using current diagnostic methods, the prostate specific antigen (PSA) blood test and histological grading of prostate tissue needle biopsies, it is often difficult to evaluate whether the patient has a PC that requires active treatment or not. READ MORE

4. 2. On diagnostic procedures in pulmonary embolism

   Author : Mårten Söderberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : CTPA; D-dimer; deep venous thrombosis; pre-test probability score; pulmonary arteriography; pulmonary embolism; venous thromboembolism; von Willebrand factor antigen; Wells score.;

   Abstract : Pulmonary embolism (PE) and deep venous thrombosis (DVT) are two entities of venous thromboembolism (VTE). PE is a common cause of mortality and morbidity. The symptoms and signs of PE are difficult to interpret, and the diagnosis is difficult to establish. READ MORE

5. 3. Thrombin activatable fibrinolysis inhibitor (TAFI) in different hemorrhagic and thrombotic conditions

   Author : Jovan P Antovic; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Thrombin activatable fibrinolysis inhibitor TAFI ; coagulation; fibrinolysis; thrombin; plasmin; factor V Leiden; hemophilia; von Willebrand disease; diabetes mellitus; preeclampsia;

   Abstract : Until recently the coagulation and fibrinolytic systems were usually considered as separate entities. Accounts of a fibrinolysis inhibitor that is generated by thrombin shed more light on this field and changed the concept by giving thrombin, the pivotal enzyme in hemostasis, another important role in the down-regulation of fibrinolysis. READ MORE

6. 4. ADAMTS13 phenotype in health and disease with special reference to thrombotic thrombocytopenic purpura

   Author : Minola Manea Hedström; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; tubular cells; podocytes; kidney; plasma; ADAMTS13; thrombotic thrombocytopenic purpura; nephrology; Urologi; nefrologi; Pediatrics; Pediatri;

   Abstract : Von Willebrand factor (VWF) is synthesized and secreted by endothelial cells into the plasma as a series of multimers. VWF induces the formation of platelet plugs at sites of vascular injury and high shear stress. Biological activity is dependent on multimeric size, which is regulated in plasma by the VWF-cleaving protease ADAMTS13. READ MORE

7. 5. Hemostasis in middle-aged women with coronary heart disease

   Author : Margita Eriksson-Berg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Women; coagulation; fibrinolysis; coronary heart disease; genetics; exercise test.;

   Abstract : Inflammation and hemostasis play important roles in atherosclerotic disease. Chronic low-grade inflammation contributes to plaque vulnerability and rupture, and the subsequent thrombus formation is identified as the key mechanism in the pathogenesis of the acute coronary syndromes. READ MORE