Search for dissertations about: "white matter lesions"

Showing result 16 - 20 of 43 swedish dissertations containing the words white matter lesions.

  1. 16. Brain imaging in extremely preterm infants : relations to perinatal factors and outcome

    Author : Georgios Alexandrou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The survival of extremely preterm infants has improved over the last decades along with the advances in perinatal care. These immature children are born at a vulnerable stage of brain development, before entering the third trimester of gestation, and are at an increased risk for brain injuries, atypical brain development and subsequent adverse neurodevelopment. READ MORE

  2. 17. The Non-Invasive Brain Biopsy : Implementation and Application of Quantitative Magnetic Resonance Spectroscopy on Healthy and Diseased Human Brain

    Author : Anders Tisell; Peter Lundberg; Marcel Warntjes; Anne-Marie Landtblom; Örjan Smedby; Jan Weis; Linköpings universitet; []
    Keywords : ;

    Abstract : Introduction: In this thesis, one of the major objectives was to implement a method for (absolute) quantitative magnetic resonance spectroscopy (qMRS) of the human brain, intended for clinical use. The implemented method was based on standard spatially selective MRS sequences. READ MORE

  3. 18. Probing brain microstructure with multidimensional diffusion MRI: Encoding, interpretation, and the role of exchange

    Author : Björn Lampinen; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MRI; Diffusion; Human; Brain; Microstructure; Fysicumarkivet A:2021:Lampinen;

    Abstract : Diffusion MRI (dMRI) is a non-invasive probe of human brain microstructure. It is a long-standing promise to use dMRI for ‘in vivo histology’ and estimate tissue quantities. However, this faces several challenges. First, the microstructure models used for dMRI data are based on assumptions that may cause erroneous interpretations. READ MORE

  4. 19. Cardiovascular risk factors, brain structure, and cognitive decline in old age : a population-based study

    Author : Rui Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cardiovascular risk factors;

    Abstract : This doctoral thesis investigated the burden of cardiovascular risk factors among older adults (age ≥60 years) living in central Stockholm (Study I) and the associations of these risk factors with structural brain characteristics and cognitive decline in aging, taking genetic background (APOE gene) into account (Studies II, III, and IV). All studies in this thesis use data from the Swedish National study on Aging and Care in Kungsholmen (SNAC-K) and the embedded SNAC-K Magnetic Resonance Imaging (MRI) study. READ MORE

  5. 20. Quantitative Magnetic Resonance Imaging of the Brain : Applications for Tissue Segmentation and Multiple Sclerosis

    Author : Janne West; Peter Lundberg; Anne-Marie Landtblom; Marcel Jan Bertus Warntjes; Örjan Smedby; Olof Dahlqvist Leinhard; Per Thunberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Magnetic resonance imaging (MRI) is a sensitive technique for assessing white matter (WM) lesions in multiple sclerosis (MS), but there is a low correlation between MRI findings and clinical disability. Because of this, other pathological changes are of interest, including changes in normal appearing white matter (NAWM) and diffusely abnormal white matter (DAWM). READ MORE