Search for dissertations about: "white matter"

Showing result 11 - 15 of 230 swedish dissertations containing the words white matter.

  1. 11. Cerebral intraventricular hemorrhage and post-hemorrhagic ventricular dilatation in preterm infants: new mechanistic insights and potential treatment strategies

    Author : Olga Romantsik; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prematurity; Intraventricular hemorrhage; Post-hemorrhagic ventricular dilatation; White matter injury; Gray matter injury; Preterm rabbits; Extracellular hemoglobin; a-1-microglobulin; animal IVH models; High frequency ultrasound; MRI; corticogenesis;

    Abstract : Intraventricular hemorrhage (IVH) is one of the major co-morbidities of premature birth associated with post-hemorrhagic ventricular dilatation (PHVD) development, long-term neurodevelopmental impairment, behavioral problems, special educational needs, and dependency on social security.Hypothesis and aims: We believe that extravasated blood and further release of extracellular hemoglobin (Hb) are crucial in brain injury following IVH and consequent development of PHVD. READ MORE

  2. 12. Investigations of neural attractor dynamics in human visual awareness

    Author : David N. Silverstein; Pawel Herman; Martin Ingvar; Karl Friston; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; attractor dynamics; visual awareness; visual perception; visual attention; attentional blink; backward masking; gliomas; brain tumor; white matter; cell assemblies; neocortical model; threat response; fear signaling; amygdala; Biological Physics; Biologisk fysik; Computer Science; Datalogi; Tillämpad matematik och beräkningsmatematik; Applied and Computational Mathematics;

    Abstract : What we see, how we see it and what emotions may arise from stimuli has long been studied by philosophers, psychologists, medical doctors and neuroscientists. This thesis work investigates a particular view on the possible dynamics, utilizing computational models of spiking neural attractor networks. READ MORE

  3. 13. Diffusion MRI with generalised gradient waveforms : methods, models, and neuroimaging applications

    Author : Deneb Boito; Evren Özarslan; Magnus Herberthson; Anders Eklund; Ida Blystad; Frederik Laun; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Diffusion; Diffusion MRI; Microstructure; Brain; White matter; Microscopic anisotropy; Constrained optimisation;

    Abstract : The incessant, random motion of water molecules within biological tissues reveals unique information about the tissues’ structural and functional characteristics. Diffusion magnetic resonance imaging is sensitive to this random motion, and since the mid-1990s it has been extensively employed for studying the human brain. READ MORE

  4. 14. Observations on cerebral amyloid angiopathy and microvascular pathology in Alzheimer's disease and vascular dementia

    Author : Mattias Haglund; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Patologi allmän ; pathological anatomy; General pathology; Vascular dementia; Alzheimer s disease; Cerebral infarction; Locus ceruleus; White matter; Microvasculature; Cerebrovascular disease; patologisk anatomi; Ischemia; Cerebral amyloid angiopathy;

    Abstract : Dementia is a state of permanent loss of cognitive function, most commonly affecting the elderly. With a rapidly growing aged population, the spectrum of disorders that lead to dementia is exerting an ever-increasing toll on patients, families and society alike. The most common dementing disorders are Alzheimer's disease and vascular dementia. READ MORE

  5. 15. Biophysical modelling in diffusion MRI: The role of tissue microstructure and water exchange

    Author : Markus Nilsson; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diffusion; MRI; tissue microstructure; water exchange; Monte Carlo simulations; white matter;

    Abstract : Diffusion MRI is widely used to study brain structure in vivo. While this technique is often applied to investigations of brain connectivity, it can also be used to infer specific information about the tissue microstructure; for example, to estimate the axon diameter. READ MORE