Search for dissertations about: "xenograft tumour"

Showing result 1 - 5 of 17 swedish dissertations containing the words xenograft tumour.

  2. 1. Cell-based models for studying paediatric high-grade gliomas

    Author : Susanna Larsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; paediatric brain tumour; glioblastoma; glioma stem cell; primary culture; xenograft tumour; zebrafish;

    Abstract : Brain tumours are the largest group of solid tumours in children and accounts for most cancer-related deaths. Astrocytoma is the largest group, representing almost half of the brain tumours, where high-grade glioma is one of the most devastating forms with very poor prognosis due to lack of efficient treatments. READ MORE

  4. 2. The involvement of gangliosides in growth and migration of human glioblastoma cells

    Author : Kristina Hedberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gangliosides synthesis; Ganglioside expression; Glioblastoma; Migration; Proliferation; Cell culture systems; Xenograft model;

    Abstract : Human glioblastoma is a primary brain tumour with a bad prognosis. One major contributing factor is that the tumour grows in an infiltrative way. Single tumour cells, undetectable with today's techniques, invade the brain and escape therapy. READ MORE

  5. 3. Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours

    Author : Christina Swärd; Göteborgs universitet; []
    Keywords : Carcinoid; Endocrine pancreatic tumour; Neuroendocrine; Octreotide; Somatostatin receptor; Peptide receptor; Radionuclide therapy; Absorbed dose; Chromogranin A; Liver transplantation;

    Abstract : Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours Background. Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) originate from endocrine cells of the intestinal mucosa and pancreas. READ MORE

  6. 4. The significance of urokinase-type plasminogen activator (u-PA) in tumour growth and Linomide-induced upregulation of u-PA's endogenous inhibitor PAI-2

    Author : Anita Billström; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reproduction; andrology; gynaecology; Obstetrics; roquinimex; Linomide; cancer; prostate cancer; PAI-2; plasmin; Plasminogen activators; u-PA; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : The progressive process of tumour invasion and generation of metastases is the primary cause of death for most patients with cancer. Some of the regulatory components of this progressive process are adhesion, migration, and proteolysis. READ MORE

  7. 5. Development of individualized surgical treatments for malignant melanoma

    Author : Valerio Belgrano; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; sentinel node; isolated limb perfusion; immune-humanized xenograft mouse models; translational research;

    Abstract : Background: Cutaneous melanoma is a malignancy with an increasing incidence worldwide, especially in northern Europe. The aim of this thesis is to scrutinize the results achieved by traditional surgery and the opportunities offered by translational research for the more advanced stages of the disease. READ MORE