Search for dissertations about: "zinc complexes"
Showing result 1 - 5 of 29 swedish dissertations containing the words zinc complexes.
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1. Quantum Chemical Modelling of Biomimetic Phosphoesterase Complexes
Abstract : Phosphoesterases are a class of enzymes that catalyze hydrolysis of phosphoester bonds. They facilitate the modification of nucleic acid sequences, as well as the breakdown of rest products of warfare agents and insecticides. In this thesis, three biomimetic complexes that perform the same tasks are studied using density functional theory. READ MORE
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2. Dinuclear metal complexes modelling active sites of metallohydrolases
Abstract : To study the active sites of dinuclear metallohydrolases new metal complexes that model these sites both in structure and function have been synthesized using two new phenol based dinucleating ligands, 2-(N-isopropyl-N-((2-pyridyl)methyl)aminomethyl)-6-(N-(carboxylmethyl)-N-((2-pyridyl)methyl)aminomethyl)-4-methylphenol (IPCPMP) and 2,6-Bis[N-(N-(carboxymethyl)-N-(pyridylmethyl)amine)methyl]-4-methylphenolate (BCPMP). Both ligands contain pyridyl, tertiary amine and carboxylate groups but in IPCPMP one carboxylate donor is exchanged for a non-coordinating group yielding an unsymmetric ligand while BCPMP is symmetric with identical sets of ligands on either side of the phenol group. READ MORE
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3. Mechanistic Studies of Dinuclear Metalloenzymes - A Model Approach
Abstract : With the goal to study the mechanisms of dinuclear metalloenzymes, a new line of synthetic and computational models were prepared and studied. Mixed imidazole and carboxylate multidentate complexes were synthesized to better simulate carboxylate-rich ligand environments. READ MORE
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4. Molecular studies of Wig-1, a p53-induced zinc finger protein
Abstract : The fact that p53 is one of the most commonly mutated gene in human tumors indicates that it has a key role in tumor suppression. p53 accumulates after DNA-damage and other types of cellular stress, leading to the initiation of a p53-dependent biological response, including cell cycle arrest and apoptosis. READ MORE
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5. A nuclear magnetic resonance study of polycrystalline and surface O, O´-dialkyldithiophosphate complexes
Abstract : O, O'-dialkyldithiophosphate (dtp) complexes are known to be useful collectors of e. g. ZnS, PbS and CuS minerals in froth flotation. However, the precise surface chemistry is yet not understood. READ MORE