Search for dissertations about: "zinc-binding"

Showing result 1 - 5 of 18 swedish dissertations containing the word zinc-binding.

2. 1. Protein structure prediction : Zinc-binding sites, one-dimensional structure and remote homology

   Author : Nanjiang Shu; Sven Hovmöller; Bruce Donald; Geoff Barton; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; zinc-binding; profile; homology detection; shape string; Bioinformatics; Bioinformatik; Molecular biology; Molekylärbiologi; Biochemistry; Biokemi; Structural Chemistry; strukturkemi;

   Abstract : Predicting the three-dimensional (3D) structure of proteins is a central problem in biology. These computationally predicted 3D protein structures have been successfully applied in many fields of biomedicine, e.g. family assignments and drug discovery. READ MORE

4. 2. Prediction of zinc-binding sites in proteins and efficient protein structure description and comparison

   Author : Nanjiang Shu; Sven Hovmöller; Elisabeth Sauer-Eriksson; Alexander Luybartsev; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; zinc-binding; shape strings; protein structures; secondary structures; machine learning; Molecular biology; Molekylärbiologi; Biochemistry; Biokemi; Bioinformatics; Bioinformatik; Structural biology; Strukturbiologi; Biochemistry; biokemi; strukturbiologi; Structural Biology; Molecular Biology; molekylärbiologi;

   Abstract : A large number of proteins require certain metals to stabilize their structures or to function properly. About one third of all proteins in the Protein Data Bank (PDB) contain metals and it is estimated that approximately the same proportion of all proteins are metalloproteins. READ MORE

5. 3. Classical and Quantum Descriptions of Proteins, Lipids and Membranes

   Author : Richard Tjörnhammar; Olle Edholm; Sagar Pandit; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Quantum corrections; Coordination structure; Polarisation; Phase transitions; Kelvin differential equation; Line tension; Elastic membrane models; Molecular particle models; Zinc binding; Cholesterol and Phospholipids; Biological Physics; Biologisk fysik;

   Abstract : In this thesis the properties of proteins and membranes are studied by molecular dynamics simulations. The subject is decomposed into parts addressing free energy calculations in proteins, mechanical inclusion models for lipid bilayers, phase transitions and structural correlations in lipid bilayers and atomistic lipid bilayer models. READ MORE

6. 4. Biochemical Studies of Semenogelins with Emphasis on Zinc-Binding Properties

   Author : Magnus Jonsson; Malmö Klinisk kemi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sexualitet; sexuality; Obstetrik; gynekologi; andrologi; reproduction; andrology; gynaecology; Obstetrics; Klinisk kemi; Clinical chemistry; gel-forming proteins; surface plasmon resonance; prostate-specific antigen; protein C inhibitor; seminal plasma; zinc; semen; semenogelin; reproduktion;

   Abstract : Semenogelins I and II (SgI and SgII) are homologous and rapidly evolving proteins that have a repetitive primary structure and are synthesized mainly in the seminal vesicles. Upon ejaculation, a gelatinous coagulum is formed when the semenogelin-rich secretion from the seminal vesicles is mixed with the prostate secretion, which contains high concentrations of zinc(II) and proteases. READ MORE

7. 5. Development of improved nuclear magnetic resonance techniques and structure determination of a zinc finger peptide

   Author : Anna Hammarström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Since the functions of biological molecules are closely related to their structures, obtaining the three-dimensional structures is of great importance to the understanding of biology. Currently, the only two methods that can be used for protein structure determination at atomic resolution are X-ray crystallography and NMR spectroscopy. READ MORE