Production, purification and characterization of antibacterial biomolecules from an alkaliphilic Bacillus

Abstract: Popular Abstract in English As there is a demand for new antibacterial agents due to antimicrobial resistance, the ability of one kind of microorganisms to produce antimicrobial substances has been evaluated. Then, after determining the antibacterial-producer microorganism, the production of active compound in large scale, followed by optimization the conditions investigated. Next, the bioactive agent purified and identified with some scientific methods. Finally, the improvement effect of separated-active compound in combination with one usual antibiotic called chloramphenicol determined. Fortunately, there is a promising prospective of this combination to overcome the antimicrobial resistance problem.