Search for dissertations about: "2 1H -pyrazinone"

Showing result 6 - 10 of 104 swedish dissertations containing the words 2 1H -pyrazinone.

  2. 6. Peptidomimetics based on ring-fused 2-pyridones : probing pilicide function in uropathogenic E. coli and identification of Aβ-peptide aggregation inhibitors

    Author : Veronica Åberg; Fredrik Almqvist; Jan Kihlberg; Morten Grötli; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 2-pyridone; peptidomimetic; antibacterial; pili; Escherichia coli; virulence; amyloid; Alzheimer’s.; Organic chemistry; Organisk kemi;

    Abstract : This thesis describes the synthesis and biological evaluation of highly substituted, ring-fused 2-pyridones. The utility of the bicyclic 2-pyridones to gain fundamental insights into the disease processes of bacterial infections and Alzheimer’s disease has been investigated. READ MORE

  4. 7. Synthesis and characterization of dendritic macromolecules based on 2,2-bis(hydroxymethyl)propionic acid

    Author : Henrik Ihre; KTH; []
    Keywords : ;

    Abstract : Dendrimers are a relatively new type of macromolecules characterized by a well-defined, highly branthed, layered structure with a multitude of chain ends, adopting a globular shape at higher molar masses. Dendrimers are usually constructed from ABx type of monomers in either one of the two step-wise approaches known as thedivergentor theconvergent growth approach. READ MORE

  5. 8. Profiling Plasma Metabolite Alterations in Diet-Induced Obesity and Diabetes Using NMR Metabolomics

    Author : João Vieira; Diabetes och hjärnans funktion; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolite profiling; diet-induced obesity; type 2 diabetes mellitus; 1H-NMR spectroscopy; metabolism alterations; post-stroke recovery;

    Abstract : Diets rich in saturated fat and sedentary lifestyles markedly contribute to obesity and metabolic syndrome-related diseases, including type 2 diabetes mellitus (T2D). Metabolite profiling plays a pivotal role in understanding these metabolic diseases. READ MORE

  6. 9. Utilization of Low Voltage D-T Neutron Generators in Neutron Physics Studies

    Author : Somsorn Singkarat; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; D-T neutron generator; double-differential cross-section DDX ; n-1H scattering; directional neutron detector; time-of-flight method; natural iron; scintillation fibers; neutron energy converter;

    Abstract : In a small nuclear laboratory of a developing country a low voltage D-T neutron generator can be a very useful scientific apparatus. Such machines have been used successfully for more than 40 years in teaching and scientific research. READ MORE

  7. 10. Mesoporous Silica Formed with Triblock Copolymers

    Author : Katarina Flodström; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fysikalisk kemi; 1H NMR; TEM; SAXS; in situ; mechanism of formation; cubic Ia3d; cubic Im3m; Mesoporous; synthesis; Pluronic; SBA-16; SBA-15; hexagonal p6mm; synchrotron SAXS; Physical chemistry; amphiphilic polymers; silica;

    Abstract : The formation of highly ordered mesoporous silica materials, using PEO-PPO-PEO amphiphilic triblock copolymers (so-called Pluronics) as structure directing agents, has been studied. The materials are formed through the addition of a silica source to a polymer solution of low concentration (2.5 wt ) under acidic conditions. READ MORE