Search for dissertations about: "Horner-Wadsworth-Emmons"

Showing result 1 - 5 of 7 swedish dissertations containing the word Horner-Wadsworth-Emmons.

2. 1. Olefins from carbonyls : Development of new phosphorus-based cross-coupling reactions

   Author : Nicolas Daniele D'Imperio; Sascha Ott; Carlos Romero-Nieto; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; olefins; carbonyl olefination; phosphaalkenes; stereoselective synthesis; Wittig; Horner-Wadsworth-Emmons; McMurry;

   Abstract : Olefins, compounds containing C=C double bonds, are omnipresent in nature and serve as useful starting materials for various chemical modifications. Olefins are of crucial importance in Medicinal Chemistry and are also present in essential objects like dyes, polymers and plastics. READ MORE

4. 2. Bridging McMurry and Wittig in One-Pot : Olefins from Stereoselective, Reductive Couplings of Two Aldehydes via Phosphaalkenes

   Author : Juri Mai; Sascha Ott; Christian Müller; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; carbonyl olefination; reductive aldehyde coupling; stereoselective; organophosphorus; phosphaalkene; phosphanylphosphonate; Wittig; Horner-Wittig; Horner-Wadsworth-Emmons; McMurry; Kemi; Chemistry;

   Abstract : The formation of C=C bonds is of great importance for fundamental and industrial synthetic organic chemistry. There are many different methodologies for the construction of C=C bonds in the literature, but currently only the McMurry reaction allows the reductive coupling of two carbonyl compounds to form alkenes. READ MORE

5. 3. Synthetic approaches to chiral tetrahydropyran and tetrahydrofuran derivatives by use of asymmetric Horner-Wadsworth-Emmons reactions

   Author : Lauri Vares; KTH; []
   Keywords : ;

   Abstract : .... READ MORE

6. 4. Methods for Asymmetric Olefination Reactions; Development and Application to Natural Product Synthesis

   Author : Daniel Strand; Tobias Rein; Viresh Rawal; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antitumor agents; Asymmetric Horner-Wadsworth-Emmons; Desymmetrization; Metal-catalyzed olefination; Mucocin; Palladium-catalyzed allylic substitution; Parallel kinetic resolution; Pyranicin; Pyragonicin; Rhenium; Stereoconvergent synthesis; Stereodivergent synthesis; Stereoselective synthesis; Tetrahydropyran; Wittig reaction; Organic chemistry; Organisk kemi;

   Abstract : This thesis deals with the development and application of methods for asymmetric olefinations, in particular Horner-Wadsworth-Emmons (HWE) reactions, in the synthesis of certain natural products. Relying on asymmetric HWE reactions to access key building blocks, two natu-ral products, pyranicin and pyragonicin, were synthesized from common late intermediates. READ MORE

7. 5. Synthesis of aromatic bis- and tris(amino acids) and chiral dendrimers

   Author : Andreas Ritzén; Centrum för analys och syntes; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; HWE reaction; asymmetric hydrogenation; Heck reaction; Amino acids; chiral dendrimers;

   Abstract : A number of protected aromatic bis- and tris(amino acids) have been synthesised by catalytic asymmetric hydrogenation of the corresponding didehydroamino acid derivatives. The didehydroamino acid derivatives were prepared either by a Heck coupling of a 2-amidoacrylate with an aryl dihalide, or by Horner-Wadsworth-Emmons olefination of aromatic aldehydes with phosphonylglycine reagents. READ MORE