Search for dissertations about: "Cell scale"
Showing result 1 - 5 of 624 swedish dissertations containing the words Cell scale.
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1. Creating cell microenvironments in vitro
Abstract : Stem cells have a great potential to bring about advancements in fields like developmental biology, drug discovery, cancer biology and tissue engineering. In order to be able to use stem cells to their full potential, it is important to have control over their behavior. READ MORE
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2. Utilization of single-cell RNA-Seq and genome-scale modeling for investigating cancer metabolism
Abstract : Cancer remains a leading cause of death worldwide, and its dysregulated metabolism is a promising target for therapy. However, metabolism is complex to study – the metabolism of a cell involves the interplay of thousands of chemical reactions that are combined in different ways across tissues and cell types. READ MORE
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3. From Tissue Engineering to Engineering Education Research: Designing in vitro cell microenvironments and undergraduate research experiences
Abstract : This thesis looks at tissue engineering from two perspectives that are closely interconnected with each other: 1) Research in the discipline of tissue engineering that aims to advance our knowledge in the field, and 2) research on how students learn tissue engineering through undergraduate research.In the body, cells are constantly exposed to a concert of different signaling factors that steer their behavior. READ MORE
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4. Stereotyped B Cell Receptors in Chronic Lymphocytic Leukaemia : Implications for Antigen Selection in Leukemogenesis
Abstract : Biased immunoglobulin heavy variable (IGHV) gene usage and distinctive B-cell receptor (BCR) features have been reported in chronic lymphocytic leukaemia (CLL), which may reflect clonal selection by antigens during disease development. Furthermore, the IGHV gene mutation status distinguishes two clinical entities of CLL, where patients with unmutated IGHV genes have an inferior prognosis compared to those with mutated IGHV genes. READ MORE
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5. Molecular Mechanisms in Endothelial Cell Differentiation
Abstract : Angiogenesis is the formation of new blood vessels from the pre-existing blood vessels. Blood vessels are composed of endothelial cells and supporting musculature. Angiogenesis is regulated by numerous soluble ligands and by cell-matrix interactions. READ MORE