Search for dissertations about: "thesis in microbiology"

Showing result 1 - 5 of 969 swedish dissertations containing the words thesis in microbiology.

  1. 1. Physiology of Saccharomyces cerevisiae Producing Recombinant Insulin in Continuous Culture

    University dissertation from Chalmers University of Technology

    Author : Ali Kazemi Seresht; Chalmers tekniska högskola.; Chalmers University of Technology.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Farmaceutisk mikrobiologi; Pharmaceutical microbiology; Mikrobiologi; Microbiology; Funktionsgenomik; Functional genomics; Molekylärbiologi; Molecular biology; Genteknik inkl. funktionsgenomik; Genetic engineering including functional genomics; Keywords: heterologous protein production; prolonged chemostat; insulin analogue precursor; transcriptome; high cell density cultivation; metabolic adaptation; unfolded protein response; plasmid copy number; promoter truncation; TPI1; URA3d;

    Abstract : The yeast Saccharomyces cerevisiae has widely been used as a host for the production of heterologous proteins. High-level production of heterologous proteins is likely to impose a metabolic burden on the host cell and can thus affect various aspects of cellular physiology. READ MORE

  2. 2. Evolutionary Dynamics of Mutation and Gene Transfer in Bacteria

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Peter A Lind; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fitness cost; bacterial evolution; gene amplification; mutational biases; GC content; synonymous substitutions; horizontal gene transfer; experimental evolution; MEDICINE Microbiology; immunology; infectious diseases Microbiology Bacteriology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi Bakteriologi; NATURAL SCIENCES Biology Organism biology Microbiology; NATURVETENSKAP Biologi Organismbiologi Mikrobiologi; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi; Mikrobiologi; Microbiology;

    Abstract : The study of bacterial evolution is fundamental for addressing current problems of antibiotic resistance and emerging infectious diseases and lays a solid foundation for successful and rational design in biotechnology and synthetic biology. The main aim of this thesis is to test evolutionary hypotheses, largely based on theoretical considerations and sequence analysis, by designing scenarios in a laboratory setting to obtain experimental data. READ MORE

  3. 3. Microbial Risks in Surface Water Sources

    University dissertation from Chalmers University of Technology

    Author : Johan Åström; Chalmers tekniska högskola.; Chalmers University of Technology.; [2011]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vattenteknik; Water engineering; Matematisk statistik; Mathematical statistics; Mikrobiologi; Microbiology; Mikrobiologi; Microbiology; Miljöteknik; Environmental engineering; Pathogens; QMRA; Surface water; Flow-weighted sampling; qPCR; Bacteroidales; Bifidobacteria; Microbial source tracking; Stochastic modelling; Cryptosporidium.;

    Abstract : Microbial risks need to be properly handled for the provision of healthy drinking water. The mitigation of pathogens in the water source lowers the risk for infection associated with nominal and suboptimal drinking water treatment. READ MORE

  4. 4. The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells : Investigations in vitro and in Reactive Tissues in vivo

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Jakob Karén; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pericyte fibroblast differentiation fibrosis; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; MEDICINE Microbiology; immunology; infectious diseases Microbiology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; Medical Biochemistry; Medicinsk biokemi; Cell Research; Cellforskning; Mikrobiologi; Microbiology;

    Abstract : Pericytes are cells of mesenchymal origin located on the abluminal side, juxtapositioned to the endothelial cells in capillaries, venules and small arterioles. They are important for maintaining vessel integrity in resting tissues as well as the formation and stabilization of new vessels. READ MORE

  5. 5. Epidemiological and Bacteriological Aspects of Spotted Fever Rickettsioses in Humans, Vectors and Mammals in Sweden

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Karin Elfving; Uppsala universitet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rickettsia helvetica; ticks; cultivation; serology; polymerase chain reaction PCR ; DNA sequencing; western blot; electron microscopy; meningitis; seroprevalence;

    Abstract : Rickettsiae are obligate intracellular gram-negative bacteria transmitted by arthropod vectors. Rickettsiae sometimes cause disease in humans, typically with high fever, headache and occasionally an eschar.In Sweden, Rickettsia helvetica, belonging to the spotted fever group, is the only tick-transmitted rickettsia found free in nature. READ MORE