Nitric oxide and evaluation of different treatments in experimental colitis and inflammatory bowel disease

University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

Author: Sofie Lundberg; Karolinska Institutet.; Karolinska Institutet.; [2006]

Keywords: MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

Abstract: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder of unknown etiology of the gastrointestinal tract. Central features of IBD are increased nitric oxide (NO) generation in the gut lumen and dysfunction in regulation of leukocyte recruitment from the blood stream towards the affected tissue. This study aimed to investigate NO and the role of collagen-binding

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