Search for dissertations about: "Epigenetic inheritance"
Showing result 1 - 5 of 16 swedish dissertations containing the words Epigenetic inheritance.
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1. Stress and the Offspring : Adaptive Transgenerational Effects of Unpredictability on Behaviour and Gene Expression in Chickens (Gallus gallus)
Abstract : Environmental stress has shown to affect both the exposed individuals and the development of their offspring. Generally, it is thought that the stressed organism responds to stress by trying to adapt to it. READ MORE
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2. Inheritance of autoimmune neuroinflammation
Abstract : Multiple sclerosis (MS) is a chronic neuro-inflammatory disease with anticipated complex etiology. Susceptibility to MS is conferred by numerous genes, with very low odds ratios that explain minute fractions of disease. This indicates that unknown factors are responsible for the remaining genetic contribution, termed the missing heritability. READ MORE
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3. Heritable epigenetic responses to environmental challenges : Effects on behaviour, gene expression and DNA-methylation in the chicken
Abstract : Phenotypic variation within populations is a crucial factor in evolution and is mainly thought to be driven by heritable changes in the base sequence of DNA. Among our domesticated species we find some of the most variable species on earth today. READ MORE
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4. Epigenetic Regulation of the H19 Chromatin Insulator in Development and Disease
Abstract : The coordinated regulation of gene expression must be tightly controlled for normal development to occur. In mammals, this issue is further complicated by the requirement of both the maternal and paternal genomes for normal development, reflecting the fact that a subset of genes are monoallelically expressed depending on parental inheritance, a phenomenon known as genomic imprinting. READ MORE
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5. Involvement of epigenetic mechanisms in disease inheritance and pathogenesis of multiple sclerosis (MS) with a focus on genomic imprinting and DNA methylation in CD4+ T cells
Abstract : Multiple Sclerosis (MS) is a chronic inflammatory and neurodegenerative disease driven by autoreactive CD4+ T cells. Disease etiology is mediated by a strong interplay between genetic and environmental factors implying a role for epigenetic mechanisms. READ MORE