Search for dissertations about: "Translational stem cell research"

Showing result 1 - 5 of 7 swedish dissertations containing the words Translational stem cell research.

  1. 1. Regulation of normal and cancer cells as a base for cell cycle-targeted therapy

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Regina Miftakhova; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclin A1; Cell cycle regulation; stem cells; stem cell niche; epigenetics; cancer;

    Abstract : The majority of current treatments used for treatment of prostate cancer (PCa) and leukemia are often limited to a narrow subsets of treated patients. As such, there still remains a significant scope for gaining deeper understanding of molecular mechanisms underlying cancer metastasis for improvement of targeted treatment. READ MORE

  2. 2. Building the Bridge from Bench to Bedside: Ethical Issues in Translational Stem Cell Research

    University dissertation from Department of Medical Ethics, Lund University

    Author : Kristina Hug; Lunds universitet.; Lund University.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; research ethics; Translational stem cell research; values; experimental stem cell-based therapies; patient safety; treatment efficacy; treatment accessibility; first-in-human trials; Parkinson’s disease; Huntington’s disease; priority setting; right to withdraw; human biological material; informed consent;

    Abstract : Translational stem cell research raises many interesting ethical questions, which have, to a greater or lesser degree, been debated at an international as well as at an interdisciplinary level. Nevertheless, there is still no international consensus regarding how a number of ethical questions related to this research should be answered. READ MORE

  3. 3. Studies on renal progenitor cells and kidney cancer

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Jennifer Hansson; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Kidney cancer and renal injuries affect millions of people in the world resulting in high patient morbidity and mortality, as well as one of the most extensive medical costs for society. Upon renal injury the kidney has an endogenous ability to repair damaged tubules and restore kidney function, provided that the patient receives adequate supportive care in time. READ MORE

  4. 4. Regulatory Proteins in Progenitors and Differentiated Cells of the Human Prostate

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Jens Ceder; Lunds universitet.; Lund University.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; somatostatin; mesenchymal stem cells; transit amplifying cells; cell differentiation; adult stem cells; Prostate gland; prostatic benign hyperplasia; neuroendocrine cells; prostate cancer;

    Abstract : Prostate cancer (PC) develops from an androgen-dependent tissue that contains androgen receptors in both the stromal and glandular compartments. Surgical removal of the prostate may cure the patient, but if metastatic spread has occurred, androgen suppression therapy is the standard treatment. READ MORE

  5. 5. Prostate cancer and neuroendocrine differentiation. Molecular aspects in prostate cancer development

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Nastaran Monsef; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuron specific enolase; Prostate cancer; neuroendocrine differentiation; serotonin; hypoxia; cancer stem cell; synaptophysin; Gleason score; chromogranin A; Gleason grade;

    Abstract : Hormone refractory prostate cancer occurs when androgen-deprivation therapy (ADT) fails to stop the growth of prostate cancer for any longer. Recent studies point towards a role for neuroendocrine (NE) differentiation in the development of hormone refractory disease. READ MORE