Search for dissertations about: "Lund University."

Showing result 1 - 5 of 8488 swedish dissertations containing the words Lund University..

  1. 1. Chemogenetics, Induced Neurons and Pluripotent Stem Cells: Towards Advanced Gene and Cell Therapies Targeting Epilepsy

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Natalia Avaliani; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chemogenetics; iPS; iN; electrophysiology; gene and cell therapy; Epilepsy;

    Abstract : The complexity of the central nervous system and existence of the blood-brain barrier often causes difficulties for traditional pharmacological treatments of neurological diseases. This thesis explores the feasibility and potential for novel gene and cell therapy approaches, which hold better promise for neurological disorders, while particularly targeting epilepsy. READ MORE

  2. 2. Novel approaches to explore mechanisms of epileptic seizures - optogenetic and chemogenetic manipulation of hippocampal circuitry

    University dissertation from Experimental Epilepsy Group

    Author : Fredrik Berglind; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Seizure; epileptogenesis; optogenetics; NpHR; ChR2; DREADD; hippocampus; in vivo; mouse;

    Abstract : Epilepsy comprises a family of neurological disorders characterized by recurrent seizures, which can be highly debilitating. Up to 30% of patients with temporal lobe epilepsy, the most common form of the disorder in adults, arising in the hippocampus, cannot be effectively treated by current pharmaceuticals. READ MORE

  3. 3. SCHIZOPHRENIA IN A LONGITUDINAL PERSPECTIVE clinical and neurocognitive aspects

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Jonas Eberhard; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxikologi; farmaci; farmakognosi; toxicology; Farmakologi; pharmacognosy; pharmacy; Pharmacological sciences; Folkhälsa; epidemiologi; epidemiology; Public health; psykosomatik; klinisk psykologi; Psykiatri; psychosomatics; clinical psychology; Psychiatry; longitudinal; shared decision making; schizophrenia; cognition; prolactin; tardive dyskinesia; remission; Medicine human and vertebrates ; insight; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Popular Abstract in Swedish Schizofreni är en kronisk och handikappande sjukdom som karakteriseras av allvarliga men fluktuerande symtom, med återkommande akuta episoder. Sjukdomen är förknippad med reducerad kognitiv och social funktionsförmåga. READ MORE

  4. 4. 201Thallium SPECT; accuracy in astrocytoma diagnosis and treatment evaluation

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Kristina Källén; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The aims of the studies included in this thesis were:• to investigate the reliability of 201thallium single photon emission computed tomography (201Tl SPECT) for preoperative diagnosis and histological staging of malignant astrocytomas in comparison with CT; • to develop a method for quantification of cerebral thallium uptake, and to evaluate the quantitative measurement in comparison with CT, for astrocytoma treatment follow-up purposes; • to compare quantitative 201Tl SPECT and proton magnetic resonance spectroscopy (1H-MRS) with conventional MR imaging for astrocytoma monitoring, and to evaluate associations between change of morphological tumour characteristics during treatment and changes of cerebral thallium uptake and metabolic ratios. Results and conclusions:• High 201Tl-index, calculated as a ratio comparing tumour uptake to uptake in the contralateral hemisphere, is an indicator of highly malignant astrocytoma. READ MORE

  5. 5. Hirschsprung´s Disease & Gastroesophageal Reflux. Aspects on Two Gastrointestinal Motility Disorders in Childhood

    University dissertation from Lund University, Faculty of Medicine

    Author : Anna Gunnarsdottir; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GERD; Gastroesophageal Reflux; Duhamel pull-through; TERPT; Quality of Life; ENS; CART; Hirschsprung´s Disease; GER; pH-monitoring; Wireless; BRAVO;

    Abstract : Popular Abstract in Swedish Det enteriska nervsystemet (ENS) utgör mag-tarmkanalens eget nervsystem, ibland refererat till som “the second brain” då det uppvisar stora likheter med det centrala nervsystemet (CNS). Rubbningar i ENS ger bland annat störningar i tarmens motorik. READ MORE