Search for dissertations about: "Mycobacterium tuberculosis culture"

Showing result 1 - 5 of 14 swedish dissertations containing the words Mycobacterium tuberculosis culture.

  2. 1. Drug-resistant Mycobacterium tuberculosis in Estonia

    Author : Annika Krüüner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Tuberculosis; Estonia; M. tuberculosis; drug resistance; MDR-TB; Beijing genotype; cross-resistance; kanamycin; amikacin; rrs mutations; 16S rRNA; exposure; nosocomial transmission; mycobacterial persistence; re-infection; DST; second-line drugs; Bactec; 460; DNA fingerprinting; spoligotyping;

    Abstract : Tuberculosis (TB) infection and disease patterns among different populations are extremely heterogeneous. This thesis explores mainly by microbiological methods the epidemiology of TB in Estonia. Through the work high rates of drug resistance were found. READ MORE

  4. 2. Tuberculosis control in Sweden

    Author : Jerker Jonsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Sweden is a low tuberculosis (TB) incidence country with an incidence of 5.3 cases per 100 000 inhabitants 2017. The majority of new TB cases in Sweden are diagnosed among migrants from high TB incidence countries. READ MORE

  5. 3. Treatment optimisation of multidrug-resistant tuberculosis

    Author : Johanna Kuhlin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : A successful treatment outcome is seen in only 60% of persons treated for multidrugresistant tuberculosis (MDR-TB) worldwide, defined as resistance to both rifampicin and isoniazid. To improve these disturbingly low numbers, treatment optimisation is highly needed. READ MORE

  6. 4. Rapid assessment of drug susceptibility and mutation to resistance in mycobacterium tuberculosis Beijing type

    Author : Jim Werngren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The increasing rates of multidrug resistant tuberculosis (MDR-TB) worldwide, are seriously threatening the TB control efforts. The present thesis was aimed at increasing the knowledge about the role of different factors, such as the development of drug resistance and the efficacy of drug susceptibility assessments, in the problem with MDR-TB. READ MORE

  7. 5. Novel treatment strategies for multidrug-resistant tuberculosis

    Author : Lina Davies Forsman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tuberculosis is the leading cause of death from a single infectious agent in the world, surpassing the annual death toll of both malaria and HIV combined. The rise in multidrug-resistant tuberculosis (MDR-TB) has further exacerbated the situation, as this form of TB is more difficult and time-consuming to treat, with dismal cure rates. READ MORE