Search for dissertations about: "on anti arthritis activity"

Showing result 16 - 20 of 85 swedish dissertations containing the words on anti arthritis activity.

2. 16. Juvenile idiopathic arthritis - from macrophage to mortality

   Author : Elisabet Berthold; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Juvenile idiopathic arthritis; Epidemiology; outcome evaluation; Monocytes; Inflammation; Depression and Anxiety;

   Abstract : Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. Studies of the immunopathogenesis in JIA has mainly focused on the adaptive immune system, while less is known of the role of the monocytes. READ MORE

4. 17. Dendritic cell presentation of type II collagen

   Author : Meirav Holmdahl; Lund Dermatologi och venereologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; chromosome 2; arthritis; proteases; antigen presentation; Dendritic cell; type II collagen;

   Abstract : Type II collagen (CII) is the main protein component of cartilage and immune recognition of CII plays a critical role for the development of collagen induced arthritis (CIA), a widely used animal model for rheumatoid arthritis (RA). Antigen presentation is an important requirement for the immune response, the more efficient presentation of the antigen the better tolerance will be induced and thereby protect against arthritis. READ MORE

5. 18. Modulation of inflammation by immunostimulatory DNA

   Author : Jan Bjersing; Göteborgs universitet; []
   Keywords : CpG DNA; arthritis; phosphodiester; phosphorothioate; nucleotide modification; cytokines; chemokines; FcgammaR; B cell subsets.;

   Abstract : The aim of this thesis was to elucidate the roles of different types of DNA in inflammatory responses. We compared the immune responses to nuclease-protected phosphorothioate oligodeoxynucleotides (S-ODNs) and phosphodiester oligodeoxynucleotides (O-ODNs) that either contained or lacked CpG motifs. READ MORE

6. 19. Cardiovascular morbidity and metabolic signature in patients with rheumatoid arthritis

   Author : Mitra Nadali; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular mortality; Rheumatoid arthritis; metabolic signature;

   Abstract : Background and objectives: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease with excess risk for cardiovascular morbidity and mortality. The treatment of RA by anti-inflammatory drugs has dramatically been improved over the resent decades. READ MORE

7. 20. Predictive biomarkers in rheumatoid arthritis

   Author : Karen Hambardzumyan; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Being a very heterogeneous disease, rheumatoid arthritis (RA) is challenging for treatment. On a group level, some therapy options might be superior compared with others, however, this does not mutually exclude the less effective option to be more suitable for some patients, if the superior therapy option does not help. READ MORE