Search for dissertations about: "Phosphoinositid-30H-kinase-related-kinases PIKK"

Found 1 swedish dissertation containing the words Phosphoinositid-30H-kinase-related-kinases PIKK.

  1. 1. The role of TPPII in apoptosis control and treatment of malignant disease

    Author : Hong Xu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; proteasome; tripeptidyl peptidase II; apoptosis; inhibitor of apoptosis LAP ; p53; Phosphoinositid-30H-kinase-related-kinases PIKK ;

    Abstract : Degradation of cytosolic proteins depends largely on the proteasome. This complex contains a catalytic core (20S) and an accessory complex (19S) that recognizes ubiquitinated substrates and translocates these to the catalytic sites in the 20S particle. READ MORE