Search for dissertations about: "cortical hyper-excitability"

Found 2 swedish dissertations containing the words cortical hyper-excitability.

  1. 1. Amyotrophic lateral sclerosis (ALS) associated with superoxide dismutase 1 (SOD1) mutations in British Columbia, Canada clinical, neurophysiological and neuropathological features

    University dissertation from Umeå : Farmakologi och klinisk neurovetenskap

    Author : Heather G. Stewart; Umeå universitet.; [2005]
    Keywords : ALS; SOD1; complete penetrance; incomplete penetrance; mis-diagnosis; upper motor neuron; clinical neurophysiology; transcranial magnetic stimulation; peristimulus time histogram; corticospinal pathway; cortical inhibition; cortical hyper-excitability;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by loss of motor neurons and their supporting cells in the brain, brainstem and spinal cord, resulting in muscle paresis and paralysis including the bulbar (speech, chewing, swallowing) and respiratory muscles. The average age at onset is 55 years, and death due to respiratory failure occurs 2-5 years after symptom onset in ~ 85% of cases. READ MORE

  2. 2. On the Nature of β-Amyloid at Synapses

    University dissertation from Lund University: Faculty of Medicine

    Author : Isak Martinsson; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; synapses; APP knockout; beta-Amyloid;

    Abstract : Alzheimer’s disease is an aging related disorder of the mind, accountable for 60-80 percent of all cases of dementia. With its insidious progression and the decline of cognitive abilities, this disease is a major challenge for our society as a whole. READ MORE