Search for dissertations about: "MEDICIN Mikrobiologi"

Showing result 1 - 5 of 1205 swedish dissertations containing the words MEDICIN Mikrobiologi.

  1. 1. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes

    University dissertation from Linköping University Electronic Press

    Author : Johanna Raffetseder; Linköpings universitet.; Linköpings universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacterium tuberculosis; tuberculosis; macrophage; innate immunity; host-pathogen interaction; antibiotic tolerance; phagosomal maturation; bacterial phenotype; dormancy; persistence; virulence factor; ESAT-6; ESX-1;

    Abstract : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. READ MORE

  2. 2. Evolutionary Dynamics of Mutation and Gene Transfer in Bacteria

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Peter A Lind; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fitness cost; bacterial evolution; gene amplification; mutational biases; GC content; synonymous substitutions; horizontal gene transfer; experimental evolution; MEDICINE Microbiology; immunology; infectious diseases Microbiology Bacteriology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi Bakteriologi; NATURAL SCIENCES Biology Organism biology Microbiology; NATURVETENSKAP Biologi Organismbiologi Mikrobiologi; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi; Mikrobiologi; Microbiology;

    Abstract : The study of bacterial evolution is fundamental for addressing current problems of antibiotic resistance and emerging infectious diseases and lays a solid foundation for successful and rational design in biotechnology and synthetic biology. The main aim of this thesis is to test evolutionary hypotheses, largely based on theoretical considerations and sequence analysis, by designing scenarios in a laboratory setting to obtain experimental data. READ MORE

  3. 3. Molecular epidemiology of coagulase-negative staphylococci in hospitals and in the community

    University dissertation from Umeå : Umeå university

    Author : Micael Widerström; Umeå universitet.; Umeå universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; staphylococcus epidermidis; staphylococcus saprophyticus; electrophoresis; gel; pulsed-field; genetic diversity; methicillin-resistance; UTI; drug resistance; multiple; bacterial; epidemiology; molecular; cross infection; molecular sequence data; MEDICINE Microbiology; immunology; infectious diseases Microbiology Medical microbiology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi Medicinsk mikrobiologi; MEDICINE Microbiology; immunology; infectious diseases Microbiology Clinical bacteriology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi Klinisk bakteriologi; MEDICINE Microbiology; immunology; infectious diseases Infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Infektionssjukdomar; klinisk bakteriologi; Clinical Bacteriology; mikrobiologi; Microbiology; Infectious Diseases; infektionssjukdomar;

    Abstract : BackgroundCoagulase-negative staphylococci (CoNS) and in particular Staphylococcus epidermidis have emerged as major pathogens primarily causing nosocomial infections in patients with indwelling medical devices. These infections are often caused by multidrug-resistant strains of S. epidermidis (MDRSE). READ MORE

  4. 4. Hidden Diversity Revealed Genomic, Transcriptomic and Functional Studies of Diplomonads

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Jon Jerlström-Hultqvist; Uppsala universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Giardia intestinalis; Spironucleus salmonicida; Spironucleus barkhanus; intestinal parasite; hydrogenosome; mitosome; lateral gene transfer; horizontal gene transfer; diplomonad; metamonad; sexual recombination; transfection; protein complex purification; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Abstract : The diplomonads are a diverse group of eukaryotic microbes found in oxygen limited environments such as the intestine of animals were they may cause severe disease. Among them, the prominent human parasite Giardia intestinalis non-invasively colonizes the small intestine of humans and animals where it induces the gastrointestinal disease giardiasis. READ MORE

  5. 5. The discovery of antiviral compounds targeting adenovirus and herpes simplex virus assessment of synthetic compounds and natural products

    University dissertation from Umeå : Umeå Universitet

    Author : Mårten Strand; Umeå universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; virology; antiviral; adenovirus; herpes simplex virus; small molecule; inhibitor; hsv; drug discovery; medicinsk virologi; Medical Virology; läkemedelskemi; läkemedelskemi; mikrobiologi; Microbiology;

    Abstract : There is a need for new antiviral drugs. Especially for the treatment of adenovirus infections, since no approved anti-adenoviral drugs are available. Adenovirus infections in healthy persons are most often associated with respiratory disease, diarrhea and infections of the eye. These infections can be severe, but are most often self-limiting. READ MORE