Search for dissertations about: "YopH"
Showing result 1 - 5 of 10 swedish dissertations containing the word YopH.
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1. Antiphagocytosis by Yersinia pseudotuberculosis : role of the YopH target proteins
Abstract : The enteropathogenic bacterium Yersinia pseudotuberculosis binds to β1 integrins on a host cell via its surface protein invasin. This event stimulates signal transduction to the actin cytoskeleton of the eukaryotic cell, which allows the cell to engulf the bacterium that is attached to its surface. However, the pathogen Y. READ MORE
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2. Effects of invasin and YopH of Yersinia pseudotuberculosis on host cell signaling
Abstract : Integrins are a large family of membrane-spanning heterodimeric (αβ) receptors that bind to ligands on other cells or to extracellular matrix (ECM) proteins. These receptors mediate bidirectional signaling over the cell membrane to induce signaling cascades mediating functions as cell adhesion, spreading and migration. READ MORE
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3. Timing and targeting of Type III secretion translocation of virulence effectors in Yersinia
Abstract : The Type III secretion system (T3SS) is an important virulence mechanism that allows pathogenic bacteria to translocate virulence effectors directly into the cytoplasm of eukaryotic host cells to manipulate the host cells in favor of the pathogen. Enteropathogenic Yersinia pseudotuberculosis use a T3SS to translocate effectors, Yops, that prevent phagocytosis by immune cells, and is largely dependent on it to establish and sustain an infection in the lymphoid tissues of a mammalian host. READ MORE
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4. Inhibition of phagocyte signaling by the Yersinia virulence protein YopH
Abstract : Yersinia pseudotuberculosis evades the immediate immune defense of a host organism by inhibiting bactericidal functions of phagocytes, including phagocytosis, cytokine release, and the oxidative burst. Consequently, this pathogen can survive and multiply in lymphatic tissues. An ensemble of proteins called Yops are involved in the virulence of Y. READ MORE
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5. Interactions between Yersinia pseudotuberculosis and host cells - role of invasin and YopH
Abstract : .... READ MORE