Search for dissertations about: "nucleosome"
Showing result 1 - 5 of 46 swedish dissertations containing the word nucleosome.
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1. DNA Tetraplexes and Nucleosome Positioning Sequences
Abstract : All eukaryotic organisms package their genomes into a nucleoprotein complex known as chromatin, whose major constituents are the DNA and proteins known as histones. The non-covalent association of histones with DNA results in considerable compaction and allows the organisation of the genome into the cell nucleus. READ MORE
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2. Chromatin Structure: Nucleosome Formation and Positioning
Abstract : In all eukaryotic cells the DNA is complexed with a group of highly basic histone proteins forming nucleosomes and higher order chromatin structures. In the nucleosome the DNA is tightly wrapped, almost two turns, around an octamer of histone proteins. READ MORE
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3. Allosteric control of ALC1-catalyzed nucleosome remodeling
Abstract : The genetic information of eukaryotic cells is packaged inside the nucleus as chromatin. This packaging restricts access to the DNA and therefore represents a barrier for processes such as DNA replication, repair, and gene expression. READ MORE
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4. The Nucleosome as a Signal Carrying Unit : From Experimental Data to Combinatorial Models of Transcriptional Control
Abstract : The human genome consists of over 3 billion nucleotides and would be around 2 meters long if uncoiled and laid out. Each human somatic cell contains all this in their nucleus which is only around 5 µm across. This extreme compaction is largely achieved by wrapping the DNA around a histone octamer, the nucleosome. READ MORE
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5. Molecular mechanisms underlying the activation of ALC1 nucleosome remodeling
Abstract : Packaging DNA into chromatin represses essential DNA-based processes, such as transcription, DNA replication, and repair. To change the accessibility of DNA, cells have evolved a set of enzymes referred to as chromatin remodelers that act on the basic repeat unit of chromatin, the nucleosome. READ MORE