Search for dissertations about: "bone marrow mesenchymal stem cells"

Showing result 1 - 5 of 27 swedish dissertations containing the words bone marrow mesenchymal stem cells.

  1. 1. MESENCHYMAL STEM- AND STROMAL CELLS IN BONE MARROW AND OSTEOSARCOMA

    Author : Jan Claas Brune; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stem cells; stromal cells; bone marrow stem cells; tumour stroma; stroma-directed anti-tumour therapy; osteosarcoma;

    Abstract : Primary mesenchymal stem cells (MSC) play a central role in bone marrow (BM) and during haematopoiesis. Yet, the exact phenotype and spatial distribution of primary MSC in the human BM are unknown. Their cultured progeny are promising candidates for clinical applications. READ MORE

  2. 2. Biology of Human Primary Bone Marrow Mesenchymal Stromal Stem Cells

    Author : Roshanak Ghazanfari; Avdelningen för molekylär hematologi; []
    Keywords : Mesenchymal stem cells;

    Abstract : .... READ MORE

  3. 3. Immune modulation by mesenchymal stem cells

    Author : Ida Rasmusson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Mesenchymal stem cells; T cells; cytotoxic T lymphocytes; cytokines; mixed lymphocyte culture; B cells; antibody production; stem cell transplantation; acute graft versus host disease;

    Abstract : Mesenchymal stem cells (MSCs) were discovered as adherent cells in the bone marrow stroma that could form bone and stimulate hematopoiesis. Later, MSCs were shown to be hypoimmunogenic and to suppress proliferation of activated T cells. READ MORE

  4. 4. Bone marrow mesenchymal stem and progenitor cells in myeloid malignancies

    Author : Pingnan Xiao; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hematopoietic stem cells (HSCs) reside in bone marrow (BM) microenvironment / niche to self-renew and generate all types of mature blood cells in postnatal life. This process is called hematopoiesis. Normal hematopoiesis is tightly regulated by both intrinsic signaling in HSCs and extrinsic signals from BM niche. READ MORE

  5. 5. Characterisation of human fetal mesenchymal stem cells

    Author : Cecilia Götherström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Mesenchymal stem cells; fetal stem cell transplantation; intrauterine transplantation; osteogenesis imperfecta; mixed lymphocyte culture; gene array;

    Abstract : Mesenchymal stem cells (MSCs) are present in various tissues of fetal and adult origin. I isolated and expanded MSCs from human fetal 1st trimester livers and observed that they have a shorter cell doubling time compared to adult bone marrow-derived MSCs. READ MORE