Apnea and infection in neonates : Mediatory role of interleukin-1Beta and prostaglandin E2

University dissertation from Stockholm : Karolinska Institutet, Department of Women's and Children's Health

Author: Annika Olsson Hofstetter; Karolinska Institutet.; Karolinska Institutet.; [2006]

Keywords: MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; respiration; interleukin-1Beta; prostaglandin E2; newborns; rodents; brainstem;

Abstract: The breathing pattern of infants, particularly preterm infants, is often irregular or periodic and is frequently interrupted by apnea The latter represents a major concern in haematology, yet much remains unknown about its incidence, appearance, and pathophysiology. This thesis further characterizes cardiorespiratory activity in preterm infants during postnatal development and investigates the association between infection and apnea in neonates, focusing on the mediatory role of interleukin-1

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