Search for dissertations about: "argonaute"

Showing result 1 - 5 of 7 swedish dissertations containing the word argonaute.

  1. 1. A small amoeba at the crossroads of the big RNAi world MicroRNA biogenesis and Argonaute function in Dictyostelium discoideum

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Zhen Liao; Uppsala universitet.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNAi; microRNA; Argonaute protein; miRNA biogenesis; Dictyostelium discoideum; social amoeba; Dicer; development; growth; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : Small non-coding RNA (ncRNA) mediated gene silencing, known as RNAi, is a key regulatory mechanism of gene expression in eukaryotes. MicroRNAs (miRNA), one major type of small ncRNAs, are about 21nt long and bound by Argonaute proteins. READ MORE

  2. 2. The Regulatory Role of microRNAs in the Mouse and Human Brain

    University dissertation from Lund University: Faculty of Medicine

    Author : Rebecca Petri; Lund University.; Lunds universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; Argonaute; AGO-RIP; let-7; miR-125; adult neurogenesis; olfactory bulb; autophagy; transposable elements; LINE-2; Huntington’s disease;

    Abstract : microRNAs (miRNAs) are 20-24 nucleotides small, single-stranded, non-coding RNAs. They associate with Argonaute (AGO) proteins and exert their function by inhibition or degradation of messenger RNAs. READ MORE

  3. 3. Understanding virulence of Heterobasidion annosum s.l., a root rot pathogen of conifers

    University dissertation from ; Department of Forest Mycology and Plant Pathology, Swedish University of Agricultural Sciences

    Author : Yang Hu; Sveriges lantbruksuniversitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Heterobasidion annosum sensu lato (s.l.) species are destructive pathogens causing root and butt rot in conifers. The species complex consists of five species: H. READ MORE

  4. 4. The RNA exosome and the maintenance of genome integrity

    University dissertation from Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute

    Author : Judit Domingo Prim; Stockholms universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EXOSC10; RRP6; DNA damage; diRNA; DDRNA; DNA end resection; homologous recombination; molekylär biovetenskap; Molecular Bioscience;

    Abstract : The RNA exosome is a ribonucleolytic complex that acts on different RNA substrates and plays important roles in RNA metabolism. In recent years, the synthesis and the processing of RNA have been directly linked to the integrity of the genome. READ MORE

  5. 5. Systemic RNAi Relies on the Endomembrane System in Caenorhabditis elegans

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Yani Zhao; Uppsala universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Systemic RNAi; RNAi inheritance; late endosomes MVBs; SID-5; SEC-22; SYX-6; C12D8.1; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : The membrane system of a eukaryotic cell is a large and complex system handling the transport, exchange and degradation of many kinds of material. Recent research shows that double-stranded RNA (dsRNA) mediated gene silencing (RNA interference) is a membrane related process. READ MORE