Search for dissertations about: "Chemotherapy breast"
Showing result 1 - 5 of 94 swedish dissertations containing the words Chemotherapy breast.
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1. Chemosensitivity in Breast Cancer
Abstract : Breast cancer mortality in Sweden is now in decline, thanks to early detection and the wide use of adjuvant endocrine therapy and chemotherapy. While hormone receptor status is predictive of response to endocrine treatment, there is no clinically useful predictive marker of a patient’s response to chemotherapy. READ MORE
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2. Individually Tailored Toxicity-based Chemotherapy : Studies on Patients with Primary and Metastatic Breast Cancer
Abstract : Standard dosing of chemotherapy based on body surface area (BSA) results in large individual differences in toxicity due to a large inter-patient variability in pharmacokinetics (PK) and pharmacodynamics (PD). This results in under-dosing in certain patients with a potentially weaker antitumoral effect. READ MORE
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3. Quality of life and psychological reactions in women on first line chemotherapy for metastatic breast cancer - Correlations to tumour response and predictive factors
Abstract : Background: Health-related quality of life (HRQoL) is an important endpoint in clinical trials and as an aspect that must be considered in the treatment of patients with metastatic breast cancer. Treatment efficacy and toxicity are important factors for HRQoL, so it is imperative to study the effects of oncological treatment in terms of HRQoL. READ MORE
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4. Cyclin A and cyclin E as prognostic factors in early breast cancer
Abstract : Breast cancer is one of the most common malignancies in women. Due to early detection and the use of screening programs approximately 60% of all new cases lack lymph node involvement. Today, a substantial proportion of these women will be offered adjuvant systemic chemotherapy. READ MORE
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5. Clinical significance of immunohistochemistry in breast cancer diagnostics
Abstract : For patients with breast cancer, modern patient-tailored treatment depends on tumor- specific characteristics, i.e., estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor 2 (HER2), and the proliferation marker Ki67. READ MORE